Mouse anti-Human ZER1 Polyclonal Antibody | anti-ZER1 antibody

ZER1 (Protein zer-1 Homolog, Hzyg, Zyg-11 Homolog B-like Protein, ZYG, ZYG11BL, C9orf60)

Cat. Num. AAA642209

• Gene Names: ZER1; ZYG; C9orf60; ZYG11BL
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: ZER1; Polyclonal Antibody; ZER1 (Protein zer-1 Homolog; Hzyg; Zyg-11 Homolog B-like Protein; ZYG; ZYG11BL; C9orf60); Anti -ZER1 (Protein zer-1 Homolog; anti-ZER1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human ZER1.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MASDTPESLMALCTDFCLRNLDGTLGYLLDKETLRLHPDIFLPSEICDRLVNEYVELVNAACNFEPHESFFSLFSDPRSTRLTRIHLREDLVQDQDLEAIRKQDLVELYLTNCEKLSAKSLQTLRSFSHTLVSLSLFGCTNIFYEEENPGGCEDEYLVNPTCQVLVKDFTFEGFSRLRFLNLGRMIDWVPVESLLRPLNSLAALDLSGIQTSDAAFLTQWKDSLVSLVLYNMDLSDDHIRVIVQLHKLRHLDISRDRLSSYYKFKLTREVLSLFVQKLGNLMSLDISGHMILENCSISKMEEEAGQTSIEPSKSSIIPFRALKRPLQFLGLFENSLCRLTHIPAYKVSGDKNEEQVLNAIEAYTEHRPEITSRAINLLFDIARIERCNQLLRALKLVITALKCHKYDRNIQVTGSAALFYLTNSEYRSEQSVKLRRQVIQVVLNGMESYQEVTVQRNCCLTLCNFSIPEELEFQYRRVNELLLSILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVTMLKLIQKKLLDKTCDQVMEFSWSALWNITDETPDNCEMFLNFNGMKLFLDCLKEFPEKQELHRNMLGLLGNVAEVKELRPQLMTSQFISVFSNLLESKADGIEVSYNACGVLSHIMFDGPEAWGVCEPQREEVEERMWAAIQSWDINSRRNINYRSFEPILRLLPQGISPVSQHWATWALYNLVSVYPDKYCPLLIKEGGMPLLRDIIKMATARQETKEMARKVIEHCSNFKEENMDTSR

• Applicable Applications for anti-ZER1 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full-length human ZER1, aa1-766 (NP_006327.2).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of ZER1 expression in transfected 293T cell line by ZER1 polyclonal antibody. Lane 1: ZYG11BL transfected lysate (84.26kD). Lane 2: Non-transfected lysate.)

Product Categories/Family for anti-ZER1 antibody

Antibodies; Abs to Ubiquitin Ligases

NCBI and Uniprot Product Information

• NCBI GI #: 116284018
• NCBI GeneID: 10444
• UniProt Accession #: Q7Z7L7; O00156; Q5T272; Q5T273
• Molecular Weight: 88,169 Da
• NCBI Official Full Name: ZER1 protein
• NCBI Official Synonym Full Names: zyg-11 related, cell cycle regulator
• NCBI Official Symbol: ZER1
• NCBI Official Synonym Symbols: ZYG; C9orf60; ZYG11BL
• NCBI Protein Information: protein zer-1 homolog; ZYG homolog; zyg-11 homolog B-like protein
• UniProt Protein Name: Protein zer-1 homolog
• Protein Family: Protein
• UniProt Gene Name: ZER1
• UniProt Synonym Gene Names: C9orf60; ZYG; ZYG11BL
• UniProt Entry Name: ZER1_HUMAN

NCBI Description

This gene encodes a subunit of an E3 ubiquitin ligase complex that may be involved in meiosis. The encoded protein contains three leucine-rich repeat motifs. [provided by RefSeq, Nov 2012]

Uniprot Description

ZYG11BL: Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZER1-CUL2-Elongin BC. Belongs to the zyg-11 family.

Protein type: Ligase; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 9q34.11

Cellular Component: Cul2-RING ubiquitin ligase complex

Molecular Function: ubiquitin-protein ligase activity

Biological Process: regulation of ubiquitin-protein ligase activity; protein ubiquitination