Immunofluorescence (IF)
(Immunofluorescence analysis of L929 cells using ZCCHC3 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.)
Rabbit anti-Human, Mouse ZCCHC3 Polyclonal Antibody | anti-ZCCHC3 antibody
ZCCHC3 Polyclonal Antibody
Gene Names
ZCCHC3; C20orf99
Reactivity
Human, Mouse
Applications
Immunofluorescence
Purity
Affinity purification
Synonyms
ZCCHC3; Polyclonal Antibody; ZCCHC3 Polyclonal Antibody; C20orf99; anti-ZCCHC3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-ZCCHC3 antibody
Immunofluorescence (IF)
Application Notes
IF: 1:50-1:200
Immunogen
Recombinant fusion protein of human ZCCHC3 (NP_1490802)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunofluorescence (IF)
(Immunofluorescence analysis of L929 cells using ZCCHC3 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.)
Immunofluorescence (IF)
(Immunofluorescence analysis of L929 cells using ZCCHC3 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.)
Related Product Information for anti-ZCCHC3 antibody
Nucleic acid-binding protein involved in innate immune response to DNA and RNA viruses (PubMed:30193849, PubMed:30135424). Binds DNA and RNA in the cytoplasm and acts by promoting recognition of viral nucleic acids by virus sensors, such as DDX58/RIG-I, IFIH1/MDA5 and CGAS (PubMed:30193849, PubMed:30135424). Acts as a co-sensor for recognition of double-stranded DNA (dsDNA) by cGAS in the cytoplasm, thereby playing a role in innate immune response to cytosolic dsDNA and DNA virus (PubMed:30135424). Binds dsDNA and probably acts by promoting sensing of dsDNA by CGAS, leading to enhance CGAS oligomerization and activation (PubMed:30135424). Promotes sensing of viral RNA by RIG-I-like receptors proteins DDX58/RIG-I and IFIH1/MDA5 via two mechanisms: binds double-stranded RNA (dsRNA), enhancing the binding of DDX58/RIG-I and IFIH1/MDA5 to dsRNA and promotes 'Lys-63'-linked ubiquitination and subsequent activation of DDX58/RIG-I and IFIH1/MDA5.
Product Categories/Family for anti-ZCCHC3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
43,618 Da
NCBI Official Full Name
zinc finger CCHC domain-containing protein 3
NCBI Official Synonym Full Names
zinc finger, CCHC domain containing 3
NCBI Official Symbol
ZCCHC3
NCBI Official Synonym Symbols
C20orf99
NCBI Protein Information
zinc finger CCHC domain-containing protein 3
UniProt Protein Name
Zinc finger CCHC domain-containing protein 3
Protein Family
UniProt Gene Name
ZCCHC3
UniProt Synonym Gene Names
C20orf99
UniProt Entry Name
ZCHC3_HUMAN
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Product Notes
The ZCCHC3 zcchc3 (Catalog #AAA2565919) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZCCHC3 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ZCCHC3 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF). IF: 1:50-1:200. Researchers should empirically determine the suitability of the ZCCHC3 zcchc3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZCCHC3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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