Western Blot (WB)
(ZCCHC12 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ZCCHC12 antibody detected the ZCCHC12 protein (arrow).)
Rabbit anti-Human ZCCHC12 Polyclonal Antibody | anti-ZCCHC12 antibody
ZCCHC12 Antibody (C-term)
Western Blot (WB)
(ZCCHC12 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ZCCHC12 antibody detected the ZCCHC12 protein (arrow).)
Western Blot (WB)
(ZCCHC12 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ZCCHC12 antibody detected the ZCCHC12 protein (arrow).)
Li, H., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41(7):535-544(2009)
Cho, G., et al. Am. J. Med. Genet. A 146A (20), 2644-2650 (2008) :
Cho, G., et al. Mol. Cell. Biol. 28(5):1565-1572(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a downstream effector of bone morphogenetic protein (BMP) signalling. This protein contains a zinc finger domain and functions as a transcriptional coactivator. Variation in this gene may be associated with X-linked mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Uniprot Description
ZCCHC12: Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression. Belongs to the ZCCHC12 family.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: Xq24
Cellular Component: nuclear speck
Molecular Function: ligand-dependent nuclear receptor transcription coactivator activity; nucleic acid binding; zinc ion binding
Biological Process: BMP signaling pathway; transcription, DNA-dependent
Research Articles on ZCCHC12
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Product Notes
The ZCCHC12 zcchc12 (Catalog #AAA9205099) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 374-402. The ZCCHC12 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZCCHC12 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the ZCCHC12 zcchc12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZCCHC12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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