Testing Data
Rabbit ZCCHC12 Polyclonal Antibody | anti-ZCCHC12 antibody
ZCCHC12 Antibody
Gene Names
ZCCHC12; SIZN; SIZN1; PNMA7A
Reactivity
HumanPredicted: Mouse, Rat
Applications
ELISA, Immunohistochemistry
Synonyms
ZCCHC12; Polyclonal Antibody; ZCCHC12 Antibody; anti-ZCCHC12 antibody
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Predicted: Mouse, Rat
Clonality
Polyclonal
Form/Format
Purified by protein A column containing 0.02% NaN3
Sequence Length
402
Applicable Applications for anti-ZCCHC12 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-1:80,000
IHC: 1:100-500
IHC: 1:100-500
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitutionn.Avoid repeated freeze/defrost cycles
Testing Data
Testing Data
Related Product Information for anti-ZCCHC12 antibody
Rabbit polyclonal ZCCHC12(1) antibody was raised against a recombinate human ZCCHC12 protein 102-355aa (BC057841).
Product Categories/Family for anti-ZCCHC12 antibody
References
(1) Cho, G., Lim, Y. and Golden, J.A. SUMO interaction motifs in Sizn1 are required for promyelocytic leukemia protein nuclear body localization and for transcriptional activation.J. Biol. Chem. 284 (29), 19592-19600 (2009).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,369 Da
NCBI Official Full Name
zinc finger CCHC domain-containing protein 12
NCBI Official Synonym Full Names
zinc finger CCHC-type containing 12
NCBI Official Symbol
ZCCHC12
NCBI Official Synonym Symbols
SIZN; SIZN1; PNMA7A
NCBI Protein Information
zinc finger CCHC domain-containing protein 12
UniProt Protein Name
Zinc finger CCHC domain-containing protein 12
Protein Family
UniProt Gene Name
ZCCHC12
UniProt Synonym Gene Names
SIZN1
NCBI Description
This gene encodes a downstream effector of bone morphogenetic protein (BMP) signalling. This protein contains a zinc finger domain and functions as a transcriptional coactivator. Variation in this gene may be associated with X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Uniprot Description
Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression ().
Research Articles on ZCCHC12
Similar Products
Product Notes
The ZCCHC12 zcchc12 (Catalog #AAA852977) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZCCHC12 Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ZCCHC12 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). ELISA: 1:20,000-1:80,000 IHC: 1:100-500. Researchers should empirically determine the suitability of the ZCCHC12 zcchc12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZCCHC12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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