Western Blot (WB)
(Western blot analysis of ZC3H12C in rat brain tissue lysate with ZC3H12C antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Rabbit ZC3H12C Polyclonal Antibody | anti-ZC3H12C antibody
ZC3H12C Antibody
Gene Names
ZC3H12C; MCPIP3
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
ZC3H12C Antibody is affinity chromatography purified via peptide column.
Synonyms
ZC3H12C; Polyclonal Antibody; ZC3H12C Antibody; MCPIP3; KIAA1726; Probable ribonuclease ZC3H12C; MCP-induced protein 3; zinc finger CCCH-type containing 12C; anti-ZC3H12C antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
ZC3H12C Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
883
Applicable Applications for anti-ZC3H12C antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
ZC3H12C antibody can be used for detection of ZC3H12C by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
ZC3H12C antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZC3H12C.
Buffer
ZC3H12C Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
ZC3H12C antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of ZC3H12C in rat brain tissue lysate with ZC3H12C antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of ZC3H12C in rat brain tissue lysate with ZC3H12C antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Immunohistochemistry (IHC)
(Immunohistochemistry of ZC3H12C in human brain tissue with ZC3H12C antibody at 5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of ZC3H12C in human brain tissue with ZC3H12C antibody at 5 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of ZC3H12C in human brain tissue with ZC3H12C antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of ZC3H12C in human brain tissue with ZC3H12C antibody at 20 μg/mL.)
Related Product Information for anti-ZC3H12C antibody
ZC3H12C Antibody: ZC3H12C, also known as MCPIP3, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. Similar to ZC3H12A, ZC3H12C expression in macrophages is highly increased after treatment with lipopolysaccharide (LPS), suggesting it also may play a role in host immunity and inflammatory response.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
99,650 Da
NCBI Official Full Name
probable ribonuclease ZC3H12C
NCBI Official Synonym Full Names
zinc finger CCCH-type containing 12C
NCBI Official Symbol
ZC3H12C
NCBI Official Synonym Symbols
MCPIP3
NCBI Protein Information
probable ribonuclease ZC3H12C; MCP induced protein 3; MCP-induced protein 3; zinc finger CCCH domain-containing protein 12C
UniProt Protein Name
Probable ribonuclease ZC3H12C
Protein Family
UniProt Gene Name
ZC3H12C
UniProt Synonym Gene Names
KIAA1726; MCPIP3
UniProt Entry Name
ZC12C_HUMAN
Uniprot Description
ZC3H12C: May function as RNase and regulate the levels of target RNA species (Potential). Belongs to the ZC3H12 family.
Protein type: EC 3.1.-.-
Chromosomal Location of Human Ortholog: 11q22.3
Molecular Function: metal ion binding; endonuclease activity
Research Articles on ZC3H12C
Similar Products
Product Notes
The ZC3H12C zc3h12c (Catalog #AAA150752) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZC3H12C Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ZC3H12C can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). ZC3H12C antibody can be used for detection of ZC3H12C by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the ZC3H12C zc3h12c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZC3H12C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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