Goat anti-Human ZAG Polyclonal Antibody | anti-AZGP1 antibody
ZAG (Zinc-a2-Glycoprotein 1)
Gene Names
AZGP1; ZAG; ZA2G
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
ZAG; Polyclonal Antibody; ZAG (Zinc-a2-Glycoprotein 1); Anti -ZAG (Zinc-a2-Glycoprotein 1); anti-AZGP1 antibody
Host
Goat
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human ZAG.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 500ul sterile 40-50% glycerol, PBS.
Applicable Applications for anti-AZGP1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Direct ELISA and Western Blot.
Dilution: Direct ELISA: 0.5 -1.0ug/ml detection limit for rhZAG is ~ 0.3ng/well.
Western Blot: 1.0ug/ml
Dilution: Direct ELISA: 0.5 -1.0ug/ml detection limit for rhZAG is ~ 0.3ng/well.
Western Blot: 1.0ug/ml
Immunogen
NS0-derived rhZAG. (aa 21 - 298)
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-AZGP1 antibody
ZAG (zinc-a2-glycoprotein; also ZA2G) is a 40kD, secreted member of the MHC class I family of proteins. It is produced by adipocytes and various epithelial cells that generate exocrine-type secretions. ZAG is reported to stimulate lipid breakdown and thus may play a role in lipid homeostasis. Mature human ZAG is 278 amino acids (aa) in length. It contains one MHC class I antigen region (aa 26-201) and a C2-type Ig-like domain (aa 207-292). Two alternate splice forms exist; one shows a 66 aa substitution for the C-terminal 30 aa, and a second shows a nine Lys substitution for aa 151-298. Mature human ZAG is 60% aa identical to mouse ZAG.
Product Categories/Family for anti-AZGP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34,259 Da
NCBI Official Full Name
zinc-alpha-2-glycoprotein
NCBI Official Synonym Full Names
alpha-2-glycoprotein 1, zinc-binding
NCBI Official Symbol
AZGP1
NCBI Official Synonym Symbols
ZAG; ZA2G
NCBI Protein Information
zinc-alpha-2-glycoprotein; zn-alpha-2-GP; Zn-alpha2-glycoprotein; zn-alpha-2-glycoprotein; Alpha-2-glycoprotein, zinc
UniProt Protein Name
Zinc-alpha-2-glycoprotein
Protein Family
UniProt Gene Name
AZGP1
UniProt Synonym Gene Names
ZAG; ZNGP1; Zn-alpha-2-GP
UniProt Entry Name
ZA2G_HUMAN
Uniprot Description
AZGP1: Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids. Belongs to the MHC class I family.
Protein type: Secreted; Secreted, signal peptide; Cell adhesion
Chromosomal Location of Human Ortholog: 7q22.1
Cellular Component: extracellular space; extracellular region; plasma membrane; nucleus; MHC class I protein complex
Molecular Function: peptide antigen binding; protein transmembrane transporter activity; glycoprotein binding; antigen binding; ribonuclease activity
Biological Process: retinal homeostasis; antigen processing and presentation; negative regulation of cell proliferation; antigen processing and presentation of peptide antigen via MHC class I; positive regulation of T cell mediated cytotoxicity; immune response; detection of chemical stimulus involved in sensory perception of bitter taste; cell adhesion
Research Articles on AZGP1
Similar Products
Product Notes
The AZGP1 azgp1 (Catalog #AAA612038) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The ZAG (Zinc-a2-Glycoprotein 1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZAG can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Direct ELISA and Western Blot. Dilution: Direct ELISA: 0.5 -1.0ug/ml detection limit for rhZAG is ~ 0.3ng/well. Western Blot: 1.0ug/ml. Researchers should empirically determine the suitability of the AZGP1 azgp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZAG, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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