Western Blot (WB)
(Anti- YES1 Picoband antibody, MBS178302, Western blottingAll lanes: Anti YES1 (MBS178302) at 0.5ug/mlLane 1: SGC Whole Cell Lysate at 40ugLane 2: A549 Whole Cell Lysate at 40ugLane 3: HEPG2 Whole Cell Lysate at 40ugPredicted bind size: 61KDObserved bind size: 61KD)
anti-Human Yes1 Polyclonal Antibody | anti-YES1 antibody
Anti-Yes1 Antibody
Immunohistochemistry (IHC) Paraffin Concentration: 0.5-1ug/ml
Western Blot (WB)
(Anti- YES1 Picoband antibody, MBS178302, Western blottingAll lanes: Anti YES1 (MBS178302) at 0.5ug/mlLane 1: SGC Whole Cell Lysate at 40ugLane 2: A549 Whole Cell Lysate at 40ugLane 3: HEPG2 Whole Cell Lysate at 40ugPredicted bind size: 61KDObserved bind size: 61KD)
Western Blot (WB)
(Anti- YES1 Picoband antibody, MBS178302, Western blottingAll lanes: Anti YES1 (MBS178302) at 0.5ug/mlLane 1: SGC Whole Cell Lysate at 40ugLane 2: A549 Whole Cell Lysate at 40ugLane 3: HEPG2 Whole Cell Lysate at 40ugPredicted bind size: 61KDObserved bind size: 61KD)
Immunohistochemistry (IHC)
(Anti- YES1 Picoband antibody, MBS178302,IHC(P)IHC(P): Human Mammary Cancer Tissue )
Immunohistochemistry (IHC)
(Anti- YES1 Picoband antibody, MBS178302,IHC(P)IHC(P): Human Mammary Cancer Tissue )
Background: Proto-oncogene tyrosine-protein kinase Yes is an enzyme that in humans is encoded by the YES1 gene. This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. YES1 has been shown to interact with Janus kinase 2, CTNND1, RPL10 and Occludin.
NCBI and Uniprot Product Information
NCBI Description
This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]
Uniprot Description
Yes: a proto-oncogenic cytosolic tyrosine kinase of the Src family. Expressed at high levels in adult neurons, spermatozoa, platelets, and epithelial cells.
Protein type: Protein kinase, TK; Kinase, protein; EC 2.7.10.2; Protein kinase, tyrosine (non-receptor); Oncoprotein; TK group; Src family
Chromosomal Location of Human Ortholog: 18p11.31-p11.21
Cellular Component: actin filament; cytoplasm; cytosol; extrinsic to internal side of plasma membrane; focal adhesion; Golgi apparatus; microtubule organizing center; plasma membrane
Molecular Function: ATP binding; enzyme binding; epidermal growth factor receptor binding; non-membrane spanning protein tyrosine kinase activity; protein binding; protein-tyrosine kinase activity; receptor binding
Biological Process: cell differentiation; ephrin receptor signaling pathway; glucose transport; innate immune response; leukocyte migration; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein modification process; regulation of cell proliferation; regulation of vascular permeability; T cell costimulation; transmembrane receptor protein tyrosine kinase signaling pathway
Research Articles on YES1
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Product Notes
The YES1 yes1 (Catalog #AAA178302) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Yes1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Yes1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Western Blot Concentration: 0.1-0.5ug/ml Immunohistochemistry (IHC) Paraffin Concentration: 0.5-1ug/ml. Researchers should empirically determine the suitability of the YES1 yes1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Yes1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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