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Western Blot (WB)

Rabbit YES1 Polyclonal Antibody | anti-YES1 antibody

YES1 Antibody Affinity Purified

Gene Names
YES1; Yes; c-yes; HsT441; P61-YES
Reactivity
Human, Monkey, Mouse, Rat
Applications
ELISA, Western Blot
Synonyms
YES1; Polyclonal Antibody; YES1 Antibody Affinity Purified; c Yes; Cellular Yes 1 protein; HsT441; P61 YES; Proto oncogene tyrosine protein kinase YES; Proto-oncogene c-Yes; Tyrosine-protein kinase Yes; v yes 1 Yamaguchi sarcoma viral oncogene homolog 1; Viral oncogene yes 1 homolog 1; Yamaguchi sarcoma oncogene; Yes; YES1 antibody; anti-YES1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat
Clonality
Polyclonal
Form/Format
Affinity Purified
Concentration
0.55-0.75 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
543
Applicable Applications for anti-YES1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:500
Expression
Expressed in the epithelial cells of renal proximal tubules and stomach as well as hematopoietic cells in the bone marrow and spleen in the fetal tissues. In adult, expressed in epithelial cells of the renal proximal tubules and present in keratinocytes i
Determinant
Synthetic peptide taken within amino acid region 450-480 on human YES1 protein.
Molecular Function
ATP Binding, ion channel binding, non-membrane spanning protein tyrosine kinase activity, protein tyrosine kinase activity, enzyme binding
Subcellular Location
Cell membrane, Cytoplasm, cytoskeleton. (Note: Newly synthesized protein initially accumulates in the Golgi region and traffics to the Plasma membrane through the exocytic pathway)
Preparation and Storage
-20 degree C for long term storage

Western Blot (WB)

Western Blot (WB)
Related Product Information for anti-YES1 antibody
Affinity Purified tyrosine-protein kinase Yes Antibody Synthetic peptide taken within amino acid region 450-480 on human YES1 protein.
Regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation.
Product Categories/Family for anti-YES1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
60,801 Da
NCBI Official Full Name
tyrosine-protein kinase Yes
NCBI Official Synonym Full Names
YES proto-oncogene 1, Src family tyrosine kinase
NCBI Official Symbol
YES1
NCBI Official Synonym Symbols
Yes; c-yes; HsT441; P61-YES
NCBI Protein Information
tyrosine-protein kinase Yes
UniProt Protein Name
Tyrosine-protein kinase Yes
Protein Family
UniProt Gene Name
YES1
UniProt Synonym Gene Names
YES
UniProt Entry Name
YES_HUMAN

NCBI Description

This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]

Uniprot Description

Yes: a proto-oncogenic cytosolic tyrosine kinase of the Src family. Expressed at high levels in adult neurons, spermatozoa, platelets, and epithelial cells.

Protein type: Protein kinase, tyrosine (non-receptor); Protein kinase, TK; Kinase, protein; Oncoprotein; EC 2.7.10.2; TK group; Src family

Chromosomal Location of Human Ortholog: 18p11.31-p11.21

Cellular Component: actin filament; cytoplasm; cytosol; extrinsic to internal side of plasma membrane; focal adhesion; Golgi apparatus; microtubule organizing center; plasma membrane

Molecular Function: ATP binding; enzyme binding; epidermal growth factor receptor binding; non-membrane spanning protein tyrosine kinase activity; protein binding; protein-tyrosine kinase activity; receptor binding

Biological Process: cell differentiation; ephrin receptor signaling pathway; glucose transport; innate immune response; leukocyte migration; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein modification process; regulation of cell proliferation; regulation of vascular permeability; T cell costimulation; transmembrane receptor protein tyrosine kinase signaling pathway

Research Articles on YES1

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Product Notes

The YES1 yes1 (Catalog #AAA540860) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The YES1 Antibody Affinity Purified reacts with Human, Monkey, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's YES1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Dot Blot: 1:10,000 ELISA: 1:10,000 Western Blot: 1:500. Researchers should empirically determine the suitability of the YES1 yes1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "YES1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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