Western Blot (WB)
(Lane 1:Rat Liver Tissue Lysate; Lane 2:Rat Brain Tissue Lysate; Lane 3:Rat Spleen Tissue Lysate; Lane 4:SMMC Cell Lysate; Lane 5: COLO320 Cell Lysate; Lane 6: SW620 Cell Lysate; Lane 7: 293T Cell Lysate)
Rabbit YBX1 Polyclonal Antibody | anti-YBX1 antibody
YBX1 Antibody
Gene Names
YBX1; YB1; BP-8; CSDB; DBPB; YB-1; CBF-A; CSDA2; EFI-A; NSEP1; NSEP-1; MDR-NF1
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry
Purity
Affinity Chromatography
Synonyms
YBX1; Polyclonal Antibody; YBX1 Antibody; Affinity Purified Rabbit Polyclonal YBX1 Antibody; Polyclonal YBX1 antibody; Anti-YBX1 antibody; YBX-1 antibody; Y box binding protein 1 antibody; YB1 antibody; YBX 1 antibody; YBX-1; YBX 1; YB-1 antibody; anti-YBX1 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Lyophilized Form
Sequence Length
181
Applicable Applications for anti-YBX1 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC)
Immunogen
YBX1 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle regionof human CACYBP, identical to the related rat and Rabbit sequences, as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Lane 1:Rat Liver Tissue Lysate; Lane 2:Rat Brain Tissue Lysate; Lane 3:Rat Spleen Tissue Lysate; Lane 4:SMMC Cell Lysate; Lane 5: COLO320 Cell Lysate; Lane 6: SW620 Cell Lysate; Lane 7: 293T Cell Lysate)
Western Blot (WB)
(Lane 1:Rat Liver Tissue Lysate; Lane 2:Rat Brain Tissue Lysate; Lane 3:Rat Spleen Tissue Lysate; Lane 4:SMMC Cell Lysate; Lane 5: COLO320 Cell Lysate; Lane 6: SW620 Cell Lysate; Lane 7: 293T Cell Lysate)
Related Product Information for anti-YBX1 antibody
YB1 binding has an absolute requirement for the CCAAT box and relative specificity for the Y box. It has a molecular mass of 35,414 and contains 18% basic residues and putative nuclear localization signals. The YBX1 gene is mapped on 1p34.2. Ybx1 was highly expressed in mouse erythroid myeloid lymphoid clone-1 (EML), a hematopoietic precursor cell line, but that it was downregulated in myeloid progenitors and in Gmcsf-treated EML cells during myeloid differentiation. Ybx1 was expressed at high levels in myeloid leukemic cells at different developmental stages. Knockdown of YBX1 in a human leukemic cell line inhibited proliferation ability, induced apoptosis, and induced megakaryocytic differentiation in response to arsenic trioxide treatment. YBX1 is downregulated during myeloid differentiation and aberrant YBX1 expression in leukemic cells may contribute to leukemia development by blocking differentiation.
Product Categories/Family for anti-YBX1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
YBX1 protein, partial
NCBI Official Synonym Full Names
Y-box binding protein 1
NCBI Official Symbol
YBX1
NCBI Official Synonym Symbols
YB1; BP-8; CSDB; DBPB; YB-1; CBF-A; CSDA2; EFI-A; NSEP1; NSEP-1; MDR-NF1
NCBI Protein Information
nuclease-sensitive element-binding protein 1
Protein Family
NCBI Description
This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015]
Research Articles on YBX1
Similar Products
Product Notes
The YBX1 (Catalog #AAA5313045) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's YBX1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the YBX1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "YBX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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