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Western Blot (WB) (XRCC2 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the XRCC2 antibody detected the XRCC2 protein (arrow).)

Rabbit anti-Human XRCC2 Polyclonal Antibody | anti-XRCC2 antibody

XRCC2, NT (XRCC2, DNA repair protein XRCC2, X-ray repair cross-complementing protein 2) (FITC)

Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
XRCC2; Polyclonal Antibody; NT (XRCC2; DNA repair protein XRCC2; X-ray repair cross-complementing protein 2) (FITC); X-ray repair cross-complementing protein 2; anti-XRCC2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Applicable Applications for anti-XRCC2 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
XRCC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human XRCC2.
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(XRCC2 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the XRCC2 antibody detected the XRCC2 protein (arrow).)

Western Blot (WB) (XRCC2 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the XRCC2 antibody detected the XRCC2 protein (arrow).)
Related Product Information for anti-XRCC2 antibody
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents.
Product Categories/Family for anti-XRCC2 antibody
References
Liu, Y., et al. Carcinogenesis 31(10):1762-1769(2010). Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010). Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010). Monsees, G.M., et al. Breast Cancer Res. Treat. (2010). In press: Lipkin, S.M., et al. Cancer Prev Res (Phila) 3(5):597-603(2010).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
31,956 Da
NCBI Official Full Name
DNA repair protein XRCC2
NCBI Official Synonym Full Names
X-ray repair complementing defective repair in Chinese hamster cells 2
NCBI Official Symbol
XRCC2
NCBI Protein Information
DNA repair protein XRCC2; X-ray repair cross-complementing protein 2
UniProt Protein Name
DNA repair protein XRCC2
Protein Family
UniProt Gene Name
XRCC2
UniProt Entry Name
XRCC2_HUMAN

NCBI Description

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. [provided by RefSeq, Jul 2008]

Uniprot Description

XRCC2: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Belongs to the RecA family. RAD51 subfamily.

Chromosomal Location of Human Ortholog: 7q36.1

Cellular Component: centrosome; cytoplasm; replication fork

Molecular Function: DNA-dependent ATPase activity; protein binding; four-way junction DNA binding; ATP binding

Biological Process: meiosis; somitogenesis; positive regulation of neurogenesis; centrosome organization and biogenesis; in utero embryonic development; multicellular organism growth; response to gamma radiation; strand invasion; mitotic cell cycle; negative regulation of neuron apoptosis; DNA repair; double-strand break repair via homologous recombination; response to X-ray

Research Articles on XRCC2

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Product Notes

The XRCC2 xrcc2 (Catalog #AAA6364064) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The XRCC2, NT (XRCC2, DNA repair protein XRCC2, X-ray repair cross-complementing protein 2) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's XRCC2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the XRCC2 xrcc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "XRCC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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