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Western Blot (WB) (Western Blot analysis of XPNPEP2 in Human kidney tissue lysate using XPNPEP2 Rabbit pAb at dilution 1/200)

Rabbit anti-Human XPNPEP2 Polyclonal Antibody | anti-XPNPEP2 antibody

XPNPEP2 Rabbit pAb

Gene Names
XPNPEP2; APP2; AEACEI
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
XPNPEP2; Polyclonal Antibody; XPNPEP2 Rabbit pAb; X-prolyl aminopeptidase (aminopeptidase P) 2; membrane-bound; APP2; AEACEI; anti-XPNPEP2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.5mg/ml (varies by lot)
Applicable Applications for anti-XPNPEP2 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:200-1:1000
IHC-P: 1:25-1:100
Immunogen
Fusion protein of human XPNPEP2
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of XPNPEP2 in Human kidney tissue lysate using XPNPEP2 Rabbit pAb at dilution 1/200)

Western Blot (WB) (Western Blot analysis of XPNPEP2 in Human kidney tissue lysate using XPNPEP2 Rabbit pAb at dilution 1/200)

Immunohistochemistry (IHC)

(Immunohistochemistry of XPNPEP2 in paraffin-embedded Human colorectal cancer tissue using XPNPEP2 Rabbit pAb at dilution 1/35. Predicted cell location: Cell membrane)

Immunohistochemistry (IHC) (Immunohistochemistry of XPNPEP2 in paraffin-embedded Human colorectal cancer tissue using XPNPEP2 Rabbit pAb at dilution 1/35. Predicted cell location: Cell membrane)
Related Product Information for anti-XPNPEP2 antibody
Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the 'pita bread fold' family and occurs in mammalian tissues in both soluble and GPI-anchored membrane-bound forms. A membrane-bound and soluble form of this enzyme have been identified as products of two separate genes.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
75,625 Da
NCBI Official Full Name
xaa-Pro aminopeptidase 2
NCBI Official Synonym Full Names
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
NCBI Official Symbol
XPNPEP2
NCBI Official Synonym Symbols
APP2; AEACEI
NCBI Protein Information
xaa-Pro aminopeptidase 2; mAmP; membrane-bound APP; membrane-bound AmP; X-Pro aminopeptidase 2; aminoacylproline aminopeptidase; membrane-bound aminopeptidase P
UniProt Protein Name
Xaa-Pro aminopeptidase 2
UniProt Gene Name
XPNPEP2
UniProt Synonym Gene Names
Membrane-bound APP; Membrane-bound AmP; mAmP
UniProt Entry Name
XPP2_HUMAN

NCBI Description

Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the 'pita bread fold' family and occurs in mammalian tissues in both soluble and GPI-anchored membrane-bound forms. A membrane-bound and soluble form of this enzyme have been identified as products of two separate genes. [provided by RefSeq, Jul 2008]

Uniprot Description

XPNPEP2: A metalloprotease that may play a role in the inflammatory process and other reactions produced in response to injury or infection. May also play a role in the metabolism of the vasodilator bradykinin. Belongs to the peptidase M24B family.

Protein type: Membrane protein, GPI anchor; Protease; EC 3.4.11.9

Chromosomal Location of Human Ortholog: Xq25

Cellular Component: membrane; plasma membrane

Molecular Function: metallopeptidase activity; metal ion binding; aminopeptidase activity

Biological Process: proteolysis

Disease: Angioedema Induced By Ace Inhibitors, Susceptibility To

Research Articles on XPNPEP2

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Product Notes

The XPNPEP2 xpnpep2 (Catalog #AAA4759107) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The XPNPEP2 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's XPNPEP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000 IHC-P: 1:25-1:100. Researchers should empirically determine the suitability of the XPNPEP2 xpnpep2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "XPNPEP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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