Western Blot (WB)
(XK Antibody (N-term) (MBS9212173) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the XK antibody detected the XK protein (arrow).)
Rabbit XK Polyclonal Antibody | anti-XK antibody
XK Antibody (N-term)
Predicted Reactivity: Mouse, Rat
Predicted Reactivity: Mouse, Rat
Western Blot (WB)
(XK Antibody (N-term) (MBS9212173) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the XK antibody detected the XK protein (arrow).)
Western Blot (WB)
(XK Antibody (N-term) (MBS9212173) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the XK antibody detected the XK protein (arrow).)
This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorde characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins.
Claperon, A., et al. Brain Res. 1147, 12-24 (2007) :
Walker, R.H., et al. Transfusion 47(2):299-305(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Jung, H.H., et al. Transfusion 43(7):928-938(2003)
NCBI and Uniprot Product Information
NCBI Description
This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. [provided by RefSeq, Jul 2008]
Uniprot Description
XK: May be involved in sodium-dependent transport of neutral amino acids or oligopeptides. Defects in XK are the cause of McLeod syndrome (MLS). It is an X-linked multisystem disorder characterized by late onset abnormalities in the neuromuscular and hematopoietic systems. Belongs to the XK family.
Protein type: Membrane protein, multi-pass; Cell surface; Membrane protein, integral
Chromosomal Location of Human Ortholog: Xp21.1
Cellular Component: integral to membrane
Molecular Function: protein binding; transporter activity
Biological Process: cellular calcium ion homeostasis; myelination; amino acid transport; transport; regulation of axon diameter; skeletal muscle fiber development; regulation of cell size
Disease: Mcleod Syndrome
Research Articles on XK
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Product Notes
The XK xk (Catalog #AAA9212173) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 83-111. The XK Antibody (N-term) reacts with Human Predicted Reactivity: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's XK can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the XK xk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "XK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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