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Immunohistochemistry (IHC) (Anti-CAMK4 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Rabbit CAMK4 Polyclonal Antibody | anti-CAMK4 antibody

Rabbit Polyclonal (IgG) to Human CAMK4

Gene Names
CAMK4; IV; caMK; CaMK IV; CaMK-GR
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
CAMK4; Polyclonal Antibody; Rabbit Polyclonal (IgG) to Human CAMK4; Anti-CAMK4 Antibody (aa166-215) IHC-plus; CAM kinase IV; CaMK IV; CaMK-GR; CAMKIV; CaMK; CAM kinase- GR; CaM kinase-GR; CaM-KIV; Human CAMK4; anti-CAMK4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
CaMK4 Antibody detects endogenous levels of total CaMK4 protein.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
473
Applicable Applications for anti-CAMK4 antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA (1:1000), IF (1:100 - 1:500), IHC-P (10 ug/ml), WB (1:500 - 1:1000)
Target Species
Human
Immunogen Description
Synthetic peptide from human CaMK4 (aa166-215).
Immunogen
CAMK4 antibody was raised against synthetic peptide from human CaMK4 (aa166-215).
Antigen Modification
aa166-215
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C; Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Anti-CAMK4 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC) (Anti-CAMK4 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of HepG2 cells, using CaMK4 Antibody. The picture on the right is treated with the synthesized peptide.)

Immunofluorescence (IF) (Immunofluorescence of HepG2 cells, using CaMK4 Antibody. The picture on the right is treated with the synthesized peptide.)

Western Blot (WB)

(Western blot of extracts from K562 cells, treated with H2O2 100 uM 30', using CaMK4 Antibody. The lane on the right is treated with the synthesized peptide.)

Western Blot (WB) (Western blot of extracts from K562 cells, treated with H2O2 100 uM 30', using CaMK4 Antibody. The lane on the right is treated with the synthesized peptide.)
Related Product Information for anti-CAMK4 antibody
CAMK4 belongs to the CAMK1 subfamily of Serine/Threonine Kinases. CAMK4 has been implicated in long term memory, regulation of CRE dependent transcription, and in the control of mitochondrial biogenesis in skeletal muscle. Alternative splicing of CAMK4 generates a testis-specific calspermin transcript.
Product Categories/Family for anti-CAMK4 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
814
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,926 Da
NCBI Official Full Name
calcium/calmodulin-dependent protein kinase type IV
NCBI Official Synonym Full Names
calcium/calmodulin-dependent protein kinase IV
NCBI Official Symbol
CAMK4
NCBI Official Synonym Symbols
IV; caMK; CaMK IV; CaMK-GR
NCBI Protein Information
calcium/calmodulin-dependent protein kinase type IV; CAM kinase IV; caM kinase-GR; CAM kinase- GR; brain Ca++-calmodulin-dependent protein kinase type IV; brain Ca(2+)-calmodulin-dependent protein kinase type IV; calcium/calmodulin-dependent protein kinase type IV catalytic chain
UniProt Protein Name
Calcium/calmodulin-dependent protein kinase type IV
UniProt Gene Name
CAMK4
UniProt Synonym Gene Names
CAMK; CAMK-GR; CAMKIV; CaMK IV
UniProt Entry Name
KCC4_HUMAN

NCBI Description

The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. [provided by RefSeq, Jul 2008]

Uniprot Description

CAMK4: a protein kinase of the CAMK1 family. Implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. Two alternatively sliced isoforms have been described.

Protein type: EC 2.7.11.17; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; CAMK group; CAMK1 family

Chromosomal Location of Human Ortholog: 5q21.3

Cellular Component: nucleoplasm; nucleolus; cytosol

Molecular Function: calmodulin binding; calmodulin-dependent protein kinase activity; ATP binding

Biological Process: epidermal growth factor receptor signaling pathway; mitochondrion organization and biogenesis; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; regulation of T cell differentiation in the thymus; organelle organization and biogenesis; positive regulation of transcription, DNA-dependent; myeloid dendritic cell differentiation; nucleocytoplasmic transport; signal transduction; protein amino acid phosphorylation; positive regulation of protein export from nucleus; synaptic transmission; regulation of osteoclast differentiation; long-term memory; phospholipase C activation; innate immune response; nerve-nerve synaptic transmission; inflammatory response; myeloid dendritic cell cytokine production

Research Articles on CAMK4

Similar Products

Product Notes

The CAMK4 camk4 (Catalog #AAA244224) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human CAMK4 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CAMK4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA). ELISA (1:1000), IF (1:100 - 1:500), IHC-P (10 ug/ml), WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the CAMK4 camk4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CAMK4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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