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Rabbit anti-Human XK Polyclonal Antibody | anti-XK antibody

XK Antibody

Gene Names
XK; KX; NA; NAC; X1k; XKR1; MCLDS
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
XK; Polyclonal Antibody; XK Antibody; Kell complex 37 kDa component; Kx antigen; Membrane transport protein XK; XK related protein 1; XK-related protein 1; XK_HUMAN; XKR1; XRG1; anti-XK antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
XK Antibody detects endogenous levels of XK.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-XK antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human XK.
Conjugation
Unconjugated
Similarity
Belongs to the XK family.
Post Translational Modifications
Not glycosylated.
Subunit Structure
Heterodimer with Kell; disulfide-linked.
Tissue Specificity
High levels in skeletal muscle, heart, brain, and pancreas; low levels in placenta, lung, liver, and kidney.
Function
May be involved in sodium-dependent transport of neutral amino acids or oligopeptides.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-XK antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50,902 Da
NCBI Official Full Name
membrane transport protein XK
NCBI Official Synonym Full Names
X-linked Kx blood group
NCBI Official Symbol
XK
NCBI Official Synonym Symbols
KX; NA; NAC; X1k; XKR1; MCLDS
NCBI Protein Information
membrane transport protein XK; Kx antigen; neurocanthocytosis; neuroacanthocytosis; XK-related protein 1; kell complex 37 kDa component; Kell blood group precursor (McLeod phenotype); XK, Kell blood group complex subunit (McLeod syndrome)
UniProt Protein Name
Membrane transport protein XK
Protein Family
UniProt Gene Name
XK
UniProt Synonym Gene Names
XKR1; XRG1
UniProt Entry Name
XK_HUMAN

NCBI Description

This locus controls the synthesis of the Kell blood group 'precursor substance' (Kx). Mutations in this gene have been associated with McLeod syndrome, an X-linked, recessive disorder characterized by abnormalities in the neuromuscular and hematopoietic systems. The encoded protein has structural characteristics of prokaryotic and eukaryotic membrane transport proteins. [provided by RefSeq, Jul 2008]

Uniprot Description

XK: May be involved in sodium-dependent transport of neutral amino acids or oligopeptides. Defects in XK are the cause of McLeod syndrome (MLS). It is an X-linked multisystem disorder characterized by late onset abnormalities in the neuromuscular and hematopoietic systems. Belongs to the XK family.

Protein type: Cell surface; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: Xp21.1

Cellular Component: integral to membrane

Molecular Function: protein binding; transporter activity

Biological Process: myelination; cellular calcium ion homeostasis; transport; amino acid transport; regulation of axon diameter; skeletal muscle fiber development; regulation of cell size

Disease: Mcleod Syndrome

Research Articles on XK

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Product Notes

The XK xk (Catalog #AAA9630965) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The XK Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's XK can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the XK xk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "XK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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