Rabbit XCL2 Polyclonal Antibody | anti-XCL2 antibody

XCL2 Polyclonal Antibody

Cat. Num. AAA3007322

• Gene Names: XCL2; SCM1B; SCYC2; SCM-1b
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: XCL2; Polyclonal Antibody; XCL2 Polyclonal Antibody; Cytokine SCM-1 beta; C motif chemokine 2; XC chemokine ligand 2; SCYC2; anti-XCL2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: XCL2 polyclonal antibody detects endogenous levels of XCL2 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 114

• Applicable Applications for anti-XCL2 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthetic peptide corresponding to residues in Human XCL2.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of XCL2 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysateLane2:RAW264. 7 whole cell lysate Lane3:H9C2 whole cell lysate)

Related Product Information for anti-XCL2 antibody

XCL2 is a small cytokine belonging to the XC chemokine family. Chemokines are a group of cytokines. Members of this group of so-called C-Chemokines belong to the SCY family of cytokines and are designated XCL (L for ligand) followed by a number. XCL2 is the new designation of SCM-1-beta. XCL2 is highly related to another chemokine called XCL1. XCL2 gene is located on chromosome 1 in humans. XCL2 is predominantly expressed in activated T cells, but can also be found at low levels in unstimulated cells. XCL2 induces chemotaxis of cells expressing the chemokine receptor XCR1. XCL2 gene has been proposed to participate in pathways (Chemokine signaling pathway, Cytokine-cytokine receptor interaction) and processes (blood circulation, signal transduction, chemotaxis, immune response). XCL2 are expected to have molecular function (chemokine activity) and to localize in various compartments (extracellular space, extracellular region). A putative protein interactor has been described (XCR1). The spliced mRNA putatively encodes a good protein, containing small cytokines (intecrine / chemokine), interleukin-8 like domain; the complete protein appears to be secreted.

NCBI and Uniprot Product Information

• NCBI GI #: 11387207
• NCBI GeneID: 6846
• UniProt Accession #: Q9UBD3
• Molecular Weight: ~ 13kDa
• NCBI Official Full Name: Cytokine SCM-1 beta
• NCBI Official Synonym Full Names: X-C motif chemokine ligand 2
• NCBI Official Symbol: XCL2
• NCBI Official Synonym Symbols: SCM1B; SCYC2; SCM-1b
• NCBI Protein Information: cytokine SCM-1 beta
• UniProt Protein Name: Cytokine SCM-1 beta
• Protein Family: Cytokine
• UniProt Gene Name: XCL2
• UniProt Synonym Gene Names: SCYC2

Uniprot Description

XCL2: Chemotactic activity for lymphocytes but not for monocytes or neutrophils. Belongs to the intercrine gamma family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q24.2

Cellular Component: extracellular region; extracellular space

Molecular Function: CCR chemokine receptor binding; protein binding

Biological Process: blood circulation; G-protein coupled receptor protein signaling pathway; inflammatory response; lymphocyte chemotaxis; monocyte chemotaxis; neutrophil chemotaxis; positive regulation of GTPase activity; positive regulation of inflammatory response; signal transduction