Typical Testing Data/Standard Curve (for reference only)
ViraDuctin Adenovirus Transduction Kit
ViraDuctin Adenovirus Transduction Kit (10 Transductions)
Synonyms
ViraDuctin Adenovirus; ViraDuctin Adenovirus Transduction Kit (10 Transductions); ViraDuctin Adenovirus transduction kit
Preparation and Storage
Store at 4 degree C until the expiration date. DO NOT FREEZE.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for ViraDuctin Adenovirus transduction kit
Background: Recombinant adenoviruses have tremendous potential in both research and therapeutic applications. There are numerous advantages in using an adenovirus to introduce genetic material into host cells. The virus has been used to infect many mammalian cell types (both replicative and non-replicative) for high expression of the recombinant protein. Recombinant adenoviruses are especially useful for gene transfer and protein expression in cell lines that have low transfection efficiency with liposome. After entering cells, the virus remains epichromosomal (i.e. does not integrate into the host chromosome so does not activate or inactivate host genes). Recently, recombinant adenoviruses have been used to deliver RNAi into cells. A limiting step in adenoviral uptake is the entry into target cells, which is mediated by the coxsackievirus-adenovirus receptor (CAR) and cellular alphavbeta integrins. In many cell types, these receptors are either absent or expressed at low levels, leading to poor transduction efficiency by adenovirus. For instance, most stem cells and fibroblast-type cells are poorly infected by adenoviral vectors because of low expression of CAR.
Product Categories/Family for ViraDuctin Adenovirus transduction kit
References
1. Bergelson JM, Cunningham JA, Droguett G, Kurt-Jones EA, Krithivas A, Hong JS, Horwitz MS, Crowell RL, Finberg RW. (1997) Science 275, 1320-3.2. Tomko, R. P., R. Xu, and L. Philipson. (1997) Proc. Natl. Acad. Sci. USA 94, 3352-3356
1. Monick, M. et al. (2008). Constitutive ERK MAPK activity regulates macrophage ATP production and mitochondrial integrity. J. Immunol. 180:7485-7496.2. Ackerman, W. et al. (2007). Nuclear Factor-kappa B regulates inducible prostaglandin E synthase expression in human amnion mesenchymal cells. Biol. Reprod. 78: 68-76.
1. Monick, M. et al. (2008). Constitutive ERK MAPK activity regulates macrophage ATP production and mitochondrial integrity. J. Immunol. 180:7485-7496.2. Ackerman, W. et al. (2007). Nuclear Factor-kappa B regulates inducible prostaglandin E synthase expression in human amnion mesenchymal cells. Biol. Reprod. 78: 68-76.
Similar Products
Product Notes
The ViraDuctin Adenovirus (Catalog #AAA168054) is a Transduction Kit and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ViraDuctin Adenovirus, Transduction Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
