Western Blot (WB)
(Gel: 8%SDS-PAGE Lysate: 40 μ g Lane: Human fetal muscle tissue Primary antibody: 1/200 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds)
Rabbit anti-Human WNT10B Polyclonal Antibody | anti-WNT10B antibody
WNT10B Antibody
Immunohistochemistry: 1:10-1:50
Western Blot (WB)
(Gel: 8%SDS-PAGE Lysate: 40 μ g Lane: Human fetal muscle tissue Primary antibody: 1/200 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds)
Western Blot (WB)
(Gel: 8%SDS-PAGE Lysate: 40 μ g Lane: Human fetal muscle tissue Primary antibody: 1/200 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds)
NCBI and Uniprot Product Information
Uniprot Description
WNT10B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Defects in WNT10B are the cause of split-hand/foot malformation type 6 (SHFM6). SHFM is a limb malformation involving the central rays of the autopod and presenting with syndactyly, median clefts of the hands and feet, and aplasia and/or hypoplasia of the phalanges, metacarpals, and metatarsals. SHFM6 is a autosomal recessive disorder. Belongs to the Wnt family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: extracellular region; extracellular space
Molecular Function: frizzled binding; receptor agonist activity
Biological Process: cell fate commitment; chondrocyte differentiation; negative regulation of fat cell differentiation; neuron differentiation; positive regulation of apoptosis; protein stabilization; Wnt receptor signaling pathway; Wnt receptor signaling pathway through beta-catenin
Disease: Split-hand/foot Malformation 6; Tooth Agenesis, Selective, 8
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Product Notes
The WNT10B wnt10b (Catalog #AAA9415126) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The WNT10B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's WNT10B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:200-1:1000 Immunohistochemistry: 1:10-1:50. Researchers should empirically determine the suitability of the WNT10B wnt10b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WNT10B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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