Western Blot (WB)
(Western blot analysis of WIZ in rat lung tissue lysate with WIZ antibody at 1 μg/mL.)
Rabbit WIZ Polyclonal Antibody | anti-WIZ antibody
WIZ Antibody
Gene Names
WIZ; ZNF803
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
WIZ Antibody is affinity chromatography purified via peptide column.
Synonyms
WIZ; Polyclonal Antibody; WIZ Antibody; ZNF803; Protein Wiz; Widely-interspaced zinc finger-containing protein; widely interspaced zinc finger motifs; anti-WIZ antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
At least four isoforms of WIZ are known to exist; this antibody will detect all four.
Purity/Purification
WIZ Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
794
Applicable Applications for anti-WIZ antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
WIZ antibody can be used for detection of WIZ by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
WIZ antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TFF3.
Buffer
WIZ Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
WIZ antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of WIZ in rat lung tissue lysate with WIZ antibody at 1 μg/mL.)
Western Blot (WB)
(Western blot analysis of WIZ in rat lung tissue lysate with WIZ antibody at 1 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of WIZ in human brain tissue with WIZ antibody at 2.5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of WIZ in human brain tissue with WIZ antibody at 2.5 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of WIZ in human brain tissue with WIZ antibody at 20 μg/mL.)
Immunofluorescence (IF)
(Immunofluorescence of WIZ in human brain tissue with WIZ antibody at 20 μg/mL.)
Related Product Information for anti-WIZ antibody
WIZ Antibody: WIZ, also known as ZNF803, was initially identified in a mouse cerebellum cDNA library screen and its message was found to be expressed in the granule cell layers of the cerebellum as well as in the dentate gyrus and olfactory bulb. Later analysis indicates however that WIZ is ubiquitously expressed. WIZ is a nuclear protein that co-localizes with G9a, a histone methyltransferase responsible for mono- and dimethylation of H3K9 at euchromatic regions. WIZ can also associate with CtBP family proteins, known to be transcriptional co-repressors, and has been suggested to link G9a/GLP complexes to the CtBP co-repressor machinery, possibly regulating complex stability and gene silencing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
89,356 Da
NCBI Official Full Name
protein Wiz
NCBI Official Synonym Full Names
widely interspaced zinc finger motifs
NCBI Official Symbol
WIZ
NCBI Official Synonym Symbols
ZNF803
NCBI Protein Information
protein Wiz; WIZ zinc finger; zinc finger protein 803; widely-interspaced zinc finger motifs; widely-interspaced zinc finger-containing protein
UniProt Protein Name
Protein Wiz
Protein Family
UniProt Gene Name
WIZ
UniProt Synonym Gene Names
ZNF803
UniProt Entry Name
WIZ_HUMAN
Uniprot Description
WIZ: May link EHMT1 and EHMT2 histone methyltransferases to the CTBP corepressor machinery. May be involved in EHMT1-EHMT2 heterodimer formation and stabilization. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 19p13.1
Cellular Component: nucleus
Molecular Function: protein binding; metal ion binding
Biological Process: protein stabilization
Similar Products
Product Notes
The WIZ wiz (Catalog #AAA150772) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The WIZ Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's WIZ can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WIZ antibody can be used for detection of WIZ by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the WIZ wiz for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WIZ, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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