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Rabbit anti-Human, Mouse Wdr5 Polyclonal Antibody | anti-Wdr5 antibody

Wdr5 (WD Repeat-Containing Protein 5, BMP2-Induced 3-kb gene Protein, WD Repeat-Containing Protein BIG-3, Wdr5, Big, Big3) (MaxLight 650)

Gene Names
Wdr5; Big; Big-3; AA408785; AA960360; 2410008O07Rik
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
Wdr5; Polyclonal Antibody; Wdr5 (WD Repeat-Containing Protein 5; BMP2-Induced 3-kb gene Protein; WD Repeat-Containing Protein BIG-3; Big; Big3) (MaxLight 650); anti-Wdr5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes Wdr5. Species Crossreactivity: human, mouse
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Applicable Applications for anti-Wdr5 antibody
Western Blot (WB)
Application Notes
WB: 1:1000
Applications are based on unconjugated antibody.
Immunogen
KLH conjugated synthetic peptide between at the region of mouse Wdr5. Species sequence homology: rat
Conjugate
MaxLight650
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Product Categories/Family for anti-Wdr5 antibody
References
Gori F., et al. J. Biol. Chem. 276:46515-46522(2001). Carninci P., et al. Science 309:1559-1563(2005). Jiang H., et al. Cell 144:513-525(2011). Yang Y.J., et al. Cell 151:1097-1112(2012). Diao Y., et al. Cell Stem Cell 11:231-241(2012).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36,588 Da
NCBI Official Full Name
WD repeat-containing protein 5
NCBI Official Synonym Full Names
WD repeat domain 5
NCBI Official Symbol
Wdr5
NCBI Official Synonym Symbols
Big; Big-3; AA408785; AA960360; 2410008O07Rik
NCBI Protein Information
WD repeat-containing protein 5
UniProt Protein Name
WD repeat-containing protein 5
UniProt Gene Name
Wdr5
UniProt Synonym Gene Names
Big; Big3

Uniprot Description

WDR5: a WD40 repeat protein. May accelerate osteoblast differentiation. Interacts with HCFC1. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 2|2 A3

Cellular Component: histone acetyltransferase complex; histone methyltransferase complex; intracellular; nucleoplasm; nucleus

Molecular Function: histone acetyltransferase activity (H4-K16 specific); histone methyltransferase activity (H3-K4 specific); methylated histone residue binding; protein binding

Biological Process: covalent chromatin modification; histone H3-K4 methylation; neuron projection development; regulation of transcription, DNA-templated; skeletal system development; transcription, DNA-dependent

Research Articles on Wdr5

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Product Notes

The Wdr5 wdr5 (Catalog #AAA6460207) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Wdr5 (WD Repeat-Containing Protein 5, BMP2-Induced 3-kb gene Protein, WD Repeat-Containing Protein BIG-3, Wdr5, Big, Big3) (MaxLight 650) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Wdr5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the Wdr5 wdr5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Wdr5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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