Western Blot (WB)
(Western blot analysis of extracts from HEK-293 cells, using WDR19/IFT144 Antibody. The lane on the left was treated with blocking peptide.)
Rabbit WDR19/IFT144 Polyclonal Antibody | anti-WDR19/IFT144 antibody
WDR19/IFT144 Antibody
Gene Names
WDR19; ATD5; CED4; DYF-2; ORF26; Oseg6; PWDMP; SRTD5; IFT144; NPHP13
Reactivity
Human, Mouse, RatPredicted: Pig, Zebrafish, Bovine, Horse, Rabbit, Chicken
Applications
Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
WDR19/IFT144; Polyclonal Antibody; WDR19/IFT144 Antibody; DYF 2; DYF2; FLJ23127; IFT144; Intraflagellar transport 144 homolog; KIAA1638; ORF26; Oseg6; PWDMP; WD repeat containing protein 19; WD repeat domain 19; WD repeat membrane protein PWDMP; WD repeat-containing protein 19; Wdr19; WDR19_HUMAN; anti-WDR19/IFT144 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Predicted: Pig, Zebrafish, Bovine, Horse, Rabbit, Chicken
Predicted: Pig, Zebrafish, Bovine, Horse, Rabbit, Chicken
Clonality
Polyclonal
Isotype
IgG
Specificity
WDR19/IFT144 Antibody detects endogenous levels of WDR19/IFT144.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1342
Applicable Applications for anti-WDR19/IFT144 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide derived from human WDR19/IFT144.
Tissue Specificity
Some isoforms are tissue-specific. Highly expressed in the prostate. Lower expression in the cerebellum, pituitary gland, fetal lung, and pancreas. In normal prostate, expressed in both basal and luminal epithelial cells. No expression detected in fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes. Uniformed expression in prostate adenocarcinoma cells.
Fragment
Fab Fragment
Conjugate
Unconjugated
Subcellular Location
Cytoskeleton
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of extracts from HEK-293 cells, using WDR19/IFT144 Antibody. The lane on the left was treated with blocking peptide.)
Western Blot (WB)
(Western blot analysis of extracts from HEK-293 cells, using WDR19/IFT144 Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-WDR19/IFT144 antibody
Description: Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport (PubMed:20889716). Involved in cilia function and/or assembly (By similarity). Associates with the BBSome complex to mediate ciliary transport (By similarity).
Subunit Structure: Component of the IFT complex A (IFT-A) (PubMed:20889716). Interacts with BBS1 (By similarity). Interacts with TTC25 (PubMed:25860617).
Subunit Structure: Component of the IFT complex A (IFT-A) (PubMed:20889716). Interacts with BBS1 (By similarity). Interacts with TTC25 (PubMed:25860617).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 152 kDa
Predicted: 152 kDa
Predicted: 152 kDa
NCBI Official Full Name
WD repeat-containing protein 19 isoform 1
NCBI Official Synonym Full Names
WD repeat domain 19
NCBI Official Symbol
WDR19
NCBI Official Synonym Symbols
ATD5; CED4; DYF-2; ORF26; Oseg6; PWDMP; SRTD5; IFT144; NPHP13
NCBI Protein Information
WD repeat-containing protein 19
UniProt Protein Name
WD repeat-containing protein 19
UniProt Gene Name
WDR19
UniProt Synonym Gene Names
KIAA1638
UniProt Entry Name
WDR19_HUMAN
NCBI Description
The protein encoded by this gene is a member of the WD (tryptophan-aspartic acid) repeat family, which is a large family of structurally-related proteins known to participate in a wide range of cellular processes. Each WD repeat typically contains about 40 amino acids that are usually bracketed by glycine-histidine and tryptophan-aspartic acid (WD) dipeptides. This protein contains six WD repeats, three transmembrane domains, and a clathrin heavy-chain repeat. Mutations in this gene have been described in individuals with a wide range of disorders affecting function of the cilium. These disorders are known as ciliopathies, and include Jeune syndrome, Sensenbrenner syndromes, Senior-Loken syndrome, combined or isolated nephronophthisis (NPHP), and retinitis pigmentosa (RP). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Research Articles on WDR19/IFT144
Similar Products
Product Notes
The WDR19/IFT144 wdr19 (Catalog #AAA9611548) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The WDR19/IFT144 Antibody reacts with Human, Mouse, Rat Predicted: Pig, Zebrafish, Bovine, Horse, Rabbit, Chicken and may cross-react with other species as described in the data sheet. AAA Biotech's WDR19/IFT144 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the WDR19/IFT144 wdr19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WDR19/IFT144, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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