Mouse Coagulation Factor V (F5) ELISA Kit | F5 elisa kit

Mouse Coagulation Factor V (F5) ELISA Kit

Cat. Num. AAA452210

• Gene Names: F5; Cf5; Cf-5; AI173222
• Reactivity: Mouse
• Synonyms: Coagulation Factor V (F5); Mouse Coagulation Factor V (F5) ELISA Kit; FV; FVL; PCCF; Proaccelerin; Labile Factor; Factor V Leiden; Accelerator Globulin; Activated protein C cofactor; labile factor; F5 elisa kit

• Reactivity: Mouse
• Sequence Length: 2183

• Samples: Plasma.
• Assay Type: Sandwich
• Detection Range: 0.312-20ng/mL
• Sensitivity: 0.145ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 6679731
• NCBI GeneID: 14067
• NCBI Accession #: NP_032002.1
• NCBI GenBank Nucleotide #: NM_007976.3
• UniProt Accession #: O88783; Q3UTQ2; Q3UV80
• Molecular Weight: 247,230 Da
• NCBI Official Full Name: coagulation factor V preproprotein
• NCBI Official Synonym Full Names: coagulation factor V
• NCBI Official Symbol: F5
• NCBI Official Synonym Symbols: Cf5; Cf-5; AI173222
• NCBI Protein Information: coagulation factor V
• UniProt Protein Name: Coagulation factor V
• Protein Family: Coagulation factor
• UniProt Gene Name: F5

NCBI Description

This gene encodes a glycoprotein coagulation factor that plays a critical role in the process of blood coagulation and hemostasis. The encoded protein is activated by thrombin, to generate a heterodimer containing heavy and light chains held together by calcium ions. About half of the mice lacking the encoded protein die at an embryonic stage possible due to abnormal yolk-sac vasculature while the remaining animals succumbed to massive hemorrhage immediately after birth. A point mutation in this gene has been shown to cause disseminated intravascular thrombosis in the perinatal period, resulting in frequent deaths of newborn mice. [provided by RefSeq, Apr 2015]

Uniprot Description

Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin.