Rabbit VTC4 Polyclonal Antibody | anti-VTC4 antibody

Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast) VTC4 Polyclonal Antibody

• Gene Names: VTC4; PHM3; YJL012C-A
• Reactivity: Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: VTC4; Polyclonal Antibody; Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast) VTC4 Polyclonal Antibody; VTC4 Antibody; Vacuolar transporter chaperone 4; Phosphate metabolism protein 3; VTC4 PHM3 YJL012C J1345; anti-VTC4 antibody

• Host: Rabbit
• Reactivity: Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-VTC4 antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) VTC4 protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 42742256
• NCBI GeneID: 853441
• NCBI Accession #: NP_012522.2
• NCBI GenBank Nucleotide #: NM_001181446.1
• UniProt Accession #: P47075; Q7Z872; Q86ZR4; D6VWG5
• Molecular Weight: 83,155 Da
• NCBI Official Full Name: Vtc4p
• NCBI Official Symbol: VTC4
• NCBI Official Synonym Symbols: PHM3; YJL012C-A
• NCBI Protein Information: Vtc4p
• UniProt Protein Name: Vacuolar transporter chaperone 4
• Protein Family: Vacuolar transporter chaperone
• UniProt Gene Name: VTC4
• UniProt Synonym Gene Names: PHM3
• UniProt Entry Name: VTC4_YEAST

Uniprot Description

Function: Component of the vacuolar transporter chaperone (VTC) complex, which plays a role in vacuolar membrane fusion. Required for SEC18/NSF activity in SNARE priming, membrane binding of LMA1 and V0 trans-complex formation. Ref.1 Ref.6 Ref.7

Subunit structure: The VTC complex is an integral membrane heterooligomer composed of VTC1, VTC2, VTC3 and VTC4. The complex interacts with the v-SNARE NYV1 and with the V0 subunit of V-ATPase VPH1. Ref.7

Subcellular location: Vacuole membrane; Multi-pass membrane protein Ref.1.

Induction: By low phosphate. Ref.6

Miscellaneous: Present with 8710 molecules/cell in log phase SD medium.

Sequence similarities: Belongs to the VTC4 family.Contains 1 SPX domain.

Sequence caution: The sequence CAA89303.1 differs from that shown. Reason: Frameshift at position 610.