Rabbit VTA1 Polyclonal Antibody | anti-VTA1 antibody

VTA1 Rabbit Polyclonal

Cat. Num. AAA7605693

• Gene Names: VTA1; DRG1; LIP5; SBP1; DRG-1; My012; C6orf55; HSPC228
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunofluorescence
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: VTA1; Polyclonal Antibody; VTA1 Rabbit Polyclonal; anti-VTA1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 280

• Applicable Applications for anti-VTA1 antibody: ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
• Immunogen: Vps20-associated 1 homolog (S. cerevisiae)
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Western Blot (WB)

(human kidney tissue were subjected to SDS PAGE followed by western blot with MBS7605693 (VTA1 antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

• NCBI GI #: 556503352
• NCBI GeneID: 51534
• NCBI Accession #: NP_001273300.1
• NCBI GenBank Nucleotide #: NM_001286371.1
• Molecular Weight: 24,553 Da
• NCBI Official Full Name: vacuolar protein sorting-associated protein VTA1 homolog isoform b
• NCBI Official Synonym Full Names: vesicle trafficking 1
• NCBI Official Symbol: VTA1
• NCBI Official Synonym Symbols: DRG1; LIP5; SBP1; DRG-1; My012; C6orf55; HSPC228
• NCBI Protein Information: vacuolar protein sorting-associated protein VTA1 homolog
• UniProt Protein Name: Vacuolar protein sorting-associated protein VTA1 homolog
• Protein Family: Vacuolar protein sorting-associated protein
• UniProt Gene Name: VTA1
• UniProt Synonym Gene Names: C6orf55; DRG-1; LIP5; SBP1
• UniProt Entry Name: VTA1_HUMAN

NCBI Description

C6ORF55 encodes a protein involved in trafficking of the multivesicular body, an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes (Ward et al., 2005 [PubMed 15644320]).[supplied by OMIM, Mar 2008]

Uniprot Description

VTA1: Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR. Involved in HIV-1 budding. Belongs to the VTA1 family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 6q24.1

Cellular Component: cytosol; endosome membrane

Molecular Function: protein binding; protein C-terminus binding

Biological Process: autophagy; endosome transport; non-lytic virus budding; protein transport; viral infectious cycle