Rabbit anti-Human VPS51 Polyclonal Antibody | anti-VPS51 antibody

VPS51 Antibody

Cat. Num. AAA7114626

• Gene Names: VPS51; FFR; ANG2; ANG3; C11orf2; C11orf3
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: >95%; Protein G Purified
• Synonyms: VPS51; Polyclonal Antibody; VPS51 Antibody; Vacuolar protein sorting-associated protein 51 homolog; Another new gene 2 protein; Protein fat-free homolog; ANG2 C11orf2 C11orf3 FFR; anti-VPS51 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%; Protein G Purified
• Form/Format: Liquid
• Sequence Length: 782

• Applicable Applications for anti-VPS51 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: WB: 1:500-1:5000
• Immunogen Species: Human
• Immunogen: Recombinant Human Vacuolar protein sorting-associated protein 51 homolog protein (595-673AA)
• Conjugate: Non-Conjugated
• Preservative: 0.03% Proclin 300
• Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Preparation and Storage: Upon receipt, store at-20 degree C or-80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western BlotPositive WB detected in: Hela whole cell lysate, U251 whole cell lysate, A549 whole cell lysate, U87 whole cell lysateAll lanes: VPS51 antibody at 1:1000SecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 87, 73 kDaObserved band size: 87 kDa)

Product Categories/Family for anti-VPS51 antibody

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 8393009
• NCBI GeneID: 738
• NCBI Accession #: NP_037397.2
• NCBI GenBank Nucleotide #: NM_013265.4
• UniProt Accession #: Q9UID3; Q6PJV5; Q7L8A6; Q8WZ35; Q96DF4; Q96GR3
• Molecular Weight: 72,655 Da
• NCBI Official Full Name: vacuolar protein sorting-associated protein 51 homolog
• NCBI Official Synonym Full Names: VPS51, GARP complex subunit
• NCBI Official Symbol: VPS51
• NCBI Official Synonym Symbols: FFR; ANG2; ANG3; C11orf2; C11orf3
• NCBI Protein Information: vacuolar protein sorting-associated protein 51 homolog
• UniProt Protein Name: Vacuolar protein sorting-associated protein 51 homolog
• Protein Family: Vacuolar protein sorting-associated protein
• UniProt Gene Name: VPS51
• UniProt Synonym Gene Names: ANG2; C11orf2; C11orf3; FFR

NCBI Description

This gene encodes a member of the vacuolar protein sorting-associated protein 51 family. The encoded protein is a component of the Golgi-associated retrograde protein complex which acts as a tethering factor for carriers in retrograde transport from the early and late endosomes to the trans-Golgi network. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

Uniprot Description

Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN (PubMed:20685960). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).