Rabbit anti-Human VIPR2 Polyclonal Antibody | anti-VIPR2 antibody
VIPR2 Antibody (N-term)
pituitary adenylate cyclase activating polypeptide (PACAP; MIM
102980) are homologous peptides that function as neurotransmitters
and neuroendocrine hormones. While the receptors for VIP and PACAP
share homology, they differ in their substrate specificities and
expression patterns. See VIPR1 (MIM 192321) and ADCYAP1R1(MIM
102981).
Kellogg, D.L. Jr., et al. J. Appl. Physiol. 109(1):95-100(2010)
Liu, Y.J., et al. Obesity (Silver Spring) (2010) In press :
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Sjoholm, L.K., et al. J Circadian Rhythms 8, 1 (2010) :
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. [provided by RefSeq, Aug 2011]
Uniprot Description
VIPR2: This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C. Belongs to the G-protein coupled receptor 2 family.
Protein type: GPCR, family 2; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 7q36.3
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; vasoactive intestinal polypeptide receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; cell-cell signaling; negative regulation of smooth muscle cell proliferation; adenylate cyclase activation; signal transduction
Research Articles on VIPR2
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Product Notes
The VIPR2 vipr2 (Catalog #AAA9210915) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 95-123. The VIPR2 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VIPR2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the VIPR2 vipr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VIPR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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