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Rabbit anti-Human VIPR1 Polyclonal Antibody | anti-VIPR1 antibody

VIPR1 antibody

Gene Names
VIPR1; II; HVR1; RDC1; V1RG; VIPR; VIRG; VAPC1; VPAC1; VPAC1R; VIP-R-1; VPCAP1R; PACAP-R2; PACAP-R-2
Reactivity
Human
Applications
Immunohistochemistry
Purity
VIPR1 antibody was purified by affinity chromatography.
Synonyms
VIPR1; Polyclonal Antibody; VIPR1 antibody; Polyclonal VIPR1; Anti-VIPR1; type ii; pituitary adenylate cyclase activating peptide receptor 2; VIPR 1; pacap-r-2; pituitary adenylate cyclase activating polypeptide type ii receptor; pacap type ii receptor; pacap receptor; VIPR -1; anti-VIPR1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Human
Purity/Purification
VIPR1 antibody was purified by affinity chromatography.
Form/Format
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1% NaN3.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
457
Applicable Applications for anti-VIPR1 antibody
Immunohistochemistry (IHC) Paraffin
Application Notes
IHC-P: 20 ug/ml
Biological Significance
Vasoactive intestinal polypeptide receptor 1 also known as VPAC1, is a protein, that in humans is encoded by the VIPR1 gene. VPAC1 is a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
Immunogen
VIPR1 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -70 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-VIPR1 antibody
Rabbit polyclonal VIPR1 antibody
Product Categories/Family for anti-VIPR1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,201 Da
NCBI Official Full Name
vasoactive intestinal polypeptide receptor 1 isoform 1
NCBI Official Synonym Full Names
vasoactive intestinal peptide receptor 1
NCBI Official Symbol
VIPR1
NCBI Official Synonym Symbols
II; HVR1; RDC1; V1RG; VIPR; VIRG; VAPC1; VPAC1; VPAC1R; VIP-R-1; VPCAP1R; PACAP-R2; PACAP-R-2
NCBI Protein Information
vasoactive intestinal polypeptide receptor 1
UniProt Protein Name
Vasoactive intestinal polypeptide receptor 1
UniProt Gene Name
VIPR1
UniProt Synonym Gene Names
VIP-R-1; PACAP type II receptor; PACAP-R-2; PACAP-R2
UniProt Entry Name
VIPR1_HUMAN

NCBI Description

This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

VIPR1: This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38. Belongs to the G-protein coupled receptor 2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 3p22

Cellular Component: integral to plasma membrane; plasma membrane; receptor complex

Molecular Function: vasoactive intestinal polypeptide receptor activity; protein binding

Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; synaptic transmission; G-protein coupled receptor protein signaling pathway; muscle contraction; positive regulation of cell proliferation; digestion; immune response

Research Articles on VIPR1

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Product Notes

The VIPR1 vipr1 (Catalog #AAA535659) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VIPR1 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VIPR1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin. IHC-P: 20 ug/ml. Researchers should empirically determine the suitability of the VIPR1 vipr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VIPR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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