Structure
CX4152, Inhibitor
CX4152
Purity
>98% (HPLC)
Synonyms
CX4152; CX 4152; CX-4152; inhibitor
Purity/Purification
>98% (HPLC)
Target
Chemokine Receptor
Receptor
Chemokine Receptor
Chemical Name
N-(3-acetyl-2-methylnaphtho[1, 2-b]furan-5-yl)-4-(tert-butyl)benzenesulfonamide
SMILES
CC1=C(C2=C(O1)C3=CC=CC=C3C(=C2)NS(=O)(=O)C4=CC=C(C=C4)C(C)(C)C)C(=O)C
Molecular Formula
C25H25NO4S
CAS Number
333351-27-2
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for CX4152, inhibitor
A novel potent, selective CXCR2 inhibitor with IC50 of 7.6nM; displays>1,000-fold selectivity over CXCR4 (IC50>50uM); inhibits CXCR2 signaling through downregulation of surface CXCR2; significantly inhibits CXCL8-mediated neutrophil migration and LPS-induced lung inflammation in mice; inhibits CXCR2/beta-arrestin-2 association, cell migration and proliferation, and acute inflammation in mouse models.
Product Categories/Family for CX4152, inhibitor
References
1. Ha H, et al. J Chem Inf Model. 2015 Aug 24; 55 (8):1720-38.
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Product Notes
The CX4152 (Catalog #AAA3604120) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CX4152, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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