Immunohistochemistry (IHC)
(VCX1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the VCX1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human VCX1 Polyclonal Antibody | anti-VCX antibody
VCX1 Antibody (N-term)
WB~~1:1000
Immunohistochemistry (IHC)
(VCX1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the VCX1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(VCX1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the VCX1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Western Blot (WB)
(VCX1/VCX2/VCX3 Antibody (N-term) western blot analysis in A2058,MCF-7,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the VCX1/VCX2/VCX3 antibody detected the VCX1/VCX2/VCX3 protein (arrow).)
Western Blot (WB)
(VCX1/VCX2/VCX3 Antibody (N-term) western blot analysis in A2058,MCF-7,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the VCX1/VCX2/VCX3 antibody detected the VCX1/VCX2/VCX3 protein (arrow).)
multiple members on both X and Y chromosomes, and all are expressed
exclusively in male germ cells. The X-linked members are clustered
on chromosome Xp22 and Y-linked members are two identical copies of
the gene within a palindromic region on Yq11. The family members
share a high degree of sequence identity, with the exception that a
30-bp unit is tandemly repeated in X-linked members but occurs only
once in Y-linked members. The VCX gene cluster is polymorphic in
terms of copy number; different individuals may have a different
number of VCX genes. VCX/Y genes encode small and highly charged
proteins of unknown function. The presence of a putative bipartite
nuclear localization signal suggests that VCX/Y members are nuclear
proteins. This gene contains 10 repeats of the 30-bp unit.
Sy, S.M., et al. Lung Cancer 41(1):91-99(2003)
Zou, S.W., et al. Cell Res. 13(3):171-177(2003)
Fukami, M., et al. Am. J. Hum. Genet. 67(3):563-573(2000)
Lahn, B.T., et al. Hum. Mol. Genet. 9(2):311-319(2000)
NCBI and Uniprot Product Information
NCBI Description
This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 10 repeats of the 30-bp unit. [provided by RefSeq, Jul 2008]
Uniprot Description
VCX: May mediate a process in spermatogenesis or may play a role in sex ratio distortion. Belongs to the VCX/VCY family.
Chromosomal Location of Human Ortholog: Xp22
Cellular Component: nucleolus; nucleus
Molecular Function: chromatin binding
Biological Process: establishment and/or maintenance of chromatin architecture; ribosome assembly; spermatogenesis
Research Articles on VCX
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Product Notes
The VCX vcx (Catalog #AAA9212590) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The VCX1 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VCX1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). IHC~~1:50~100 WB~~1:1000. Researchers should empirically determine the suitability of the VCX vcx for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VCX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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