Western Blot (WB)
(Western blot analysis of extracts from Jurkat, MCF-7 and HUVEC cells using MBS617874.)
Rabbit anti-Human Vav3 Polyclonal Antibody
Vav3 (vav 3 oncogene, Oncogene VAV23 Guanine nucleotide exchange factor, Gef, GDP/GTP Exchange Factor, Gef)
Reactivity
Human
Applications
Western Blot
Purity
Affinity PurifiedPurified by Protein A and immunoaffinity chromatography.
Synonyms
Vav3; Polyclonal Antibody; Vav3 (vav 3 oncogene; Oncogene VAV23 Guanine nucleotide exchange factor; Gef; GDP/GTP Exchange Factor; Gef); Anti -Vav3 (vav 3 oncogene; anti-Vav3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Detects endogenous levels of total human Vav3 protein. Does not crossreact with endogenous levels of other Vav family members.
Purity/Purification
Affinity Purified
Purified by Protein A and immunoaffinity chromatography.
Purified by Protein A and immunoaffinity chromatography.
Form/Format
Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 100ug/ml BSA, 50% glycerol and less than 0.02% sodium azide.
Applicable Applications for anti-Vav3 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
Synthetic peptide (KLH-coupled) corresponding to the central sequence of human Vav3.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Western Blot (WB)
(Western blot analysis of extracts from Jurkat, MCF-7 and HUVEC cells using MBS617874.)
Western Blot (WB)
(Western blot analysis of extracts from Jurkat, MCF-7 and HUVEC cells using MBS617874.)
Related Product Information for anti-Vav3 antibody
Vav proteins belong to the Dbl family of guanine nucleotide exchange factors (GEFs) for Rho/Rac small GTPases. The three identified mammalian Vav proteins (Vav1, Vav2 and Vav3) differ in their expression. Vav1 is expressed only in hematopoietic cells and is involved in the formation of the immune synapse. Vav2 and Vav3 are more ubiquitously expressed. Vav proteins contain the Dbl homology domain, which confers GEF activity, as well as protein interaction domains that allow them to function in pathways regulating actin cytoskeleton organization (reviewed in 1). Phosphorylation stimulates the GEF activity of Vav protein towards Rho/Rac (2,3).
Product Categories/Family for anti-Vav3 antibody
NCBI and Uniprot Product Information
Similar Products
Product Notes
The Vav3 (Catalog #AAA617874) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Vav3 (vav 3 oncogene, Oncogene VAV23 Guanine nucleotide exchange factor, Gef, GDP/GTP Exchange Factor, Gef) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Vav3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the Vav3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Vav3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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