Rabbit anti-Human USP45 Polyclonal Antibody | anti-USP45 antibody
USP45 Antibody, HRP conjugated
Reactivity
Human
Applications
ELISA
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
USP45; Polyclonal Antibody; USP45 Antibody; HRP conjugated; Ubiquitin carboxyl-terminal hydrolase 45; Deubiquitinating enzyme 45; Ubiquitin thioesterase 45; Ubiquitin-specific-processing protease 45; anti-USP45 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Liquid
Sequence Length
814
Applicable Applications for anti-USP45 antibody
ELISA (EIA)
Immunogen
Recombinant human Ubiquitin carboxyl-terminal hydrolase 45 protein (1-240AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
HRP
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-82762 / sc-82763
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-USP45 antibody
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal.
References
[1]"The full-ORF clone resource of the German cDNA consortium."Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.BMC Genomics 8: 399-399(2007). [2]"The DNA sequence and analysis of human chromosome 6."Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. Beck S.Nature 425: 805-811(2003). 3[]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."The MGC Project TeamGenome Res. 14: 2121-2127(2004).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,812 Da
NCBI Official Full Name
ubiquitin carboxyl-terminal hydrolase 45 isoform a
NCBI Official Synonym Full Names
ubiquitin specific peptidase 45
NCBI Official Symbol
USP45
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase 45
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 45
Protein Family
UniProt Gene Name
USP45
UniProt Entry Name
UBP45_HUMAN
NCBI Description
The protein encoded by this gene is a deubiquitylase that binds ERCC1, the catalytic subunit of the XPF-ERCC1 DNA repair endonuclease. This endonuclease is a critical regulator of DNA repair processes, and the deubiquitylase activity of the encoded protein is important for maintaining the DNA repair ability of XPF-ERCC1. [provided by RefSeq, Sep 2016]
Uniprot Description
USP45: Belongs to the peptidase C19 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.19.12; Protease; Ubiquitin conjugating system; Ubiquitin-specific protease
Chromosomal Location of Human Ortholog: 6q16.2
Cellular Component: cytoplasm; nucleoplasm; nucleus
Molecular Function: ubiquitin-specific protease activity
Biological Process: DNA repair; protein deubiquitination
Research Articles on USP45
Similar Products
Product Notes
The USP45 usp45 (Catalog #AAA7050462) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The USP45 Antibody, HRP conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's USP45 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the USP45 usp45 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "USP45, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
