Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using at dilution 1/25.)
Rabbit anti-Human USP45 Polyclonal Antibody | anti-USP45 antibody
USP45 Antibody
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
USP45; Polyclonal Antibody; USP45 Antibody; Deubiquitinating enzyme 45; MGC14793; Ubiquitin carboxyl-terminal hydrolase 45; ubiquitin specific peptidase 45; ubiquitin specific protease 45; anti-USP45 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total USP45 protein.
Purity/Purification
Antigen Affinity Purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.3 mg/ml (varies by lot)
Sequence Length
814
Applicable Applications for anti-USP45 antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:25-1:100
Immunogen
Full length fusion protein of human USP45
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using at dilution 1/25.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using at dilution 1/25.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using at dilution 1/25.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using at dilution 1/25.)
Related Product Information for anti-USP45 antibody
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates.A wide range of enzymes facilitate the proteolytic Ub pathway, including USPs (ubiquitin specific peptidases), which are cysteine proteases that are responsible for the release of ubiquitin from a ubiquitylated substrate and precursor fusion proteins. USP45 (Ubiquitin carboxyl-terminal hydrolase 45), also known as Deubiquitinating enzyme 45, is a 819 amino acid protein that is involved in ubiquitin-dependent protein catabolism. USP45 differs from other USPs in that it contains a UBP-type zinc finger, a domain which binds ubiquitin. Although USP45 is broadly expressed, the highest levels can be found in skeletal muscle, spleen and ovary. There are three isoformsof USP45 which are produced as a result of alternative splicing.
Product Categories/Family for anti-USP45 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,812 Da
NCBI Official Full Name
ubiquitin carboxyl-terminal hydrolase 45
NCBI Official Synonym Full Names
ubiquitin specific peptidase 45
NCBI Official Symbol
USP45
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase 45
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 45
Protein Family
UniProt Gene Name
USP45
UniProt Entry Name
UBP45_HUMAN
Uniprot Description
USP45: Belongs to the peptidase C19 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.19.12; Protease; Ubiquitin conjugating system; Ubiquitin-specific protease
Chromosomal Location of Human Ortholog: 6q16.2
Cellular Component: cytoplasm; nucleoplasm; nucleus
Molecular Function: ubiquitin-specific protease activity
Biological Process: DNA repair; protein deubiquitination
Similar Products
Product Notes
The USP45 usp45 (Catalog #AAA9416188) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The USP45 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's USP45 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the USP45 usp45 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "USP45, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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