Western Blot (WB)
(Western blot analysis of USP22 Antibody (C-term) in Jurkat cell line lysates (35ug/lane). USP22 (arrow) was detected using the purified Pab.)
Rabbit anti-Human USP22 Polyclonal Antibody | anti-USP22 antibody
USP22, CT (Ubiquitin Carboxyl-terminal Hydrolase 22, Ubiquitin Thiolesterase 22, Ubiquitin-specific Processing Protease 22, Deubiquitinating Enzyme 22, KIAA1063, USP3L) (PE)
FLISA: 1:1,000
WB: 1:100-1:500
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of USP22 Antibody (C-term) in Jurkat cell line lysates (35ug/lane). USP22 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of USP22 Antibody (C-term) in Jurkat cell line lysates (35ug/lane). USP22 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
NCBI and Uniprot Product Information
Uniprot Description
USP22: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression. Belongs to the peptidase C19 family. UBP8 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin-specific protease; Ubiquitin conjugating system; Transcription, coactivator/corepressor; Cell cycle regulation; Nuclear receptor co-regulator; Protease; EC 3.4.19.12
Chromosomal Location of Human Ortholog: 17p11.2
Molecular Function: protein binding; H4 histone acetyltransferase activity; enzyme binding; ligand-dependent nuclear receptor transcription coactivator activity; zinc ion binding; cysteine-type endopeptidase activity; transcription coactivator activity; ubiquitin-specific protease activity
Biological Process: proteasomal ubiquitin-dependent protein catabolic process; embryonic development; establishment and/or maintenance of chromatin architecture; protein deubiquitination; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; histone ubiquitination; cell cycle; positive regulation of mitotic cell cycle; histone deubiquitination
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Product Notes
The USP22 usp22 (Catalog #AAA6505289) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The USP22, CT (Ubiquitin Carboxyl-terminal Hydrolase 22, Ubiquitin Thiolesterase 22, Ubiquitin-specific Processing Protease 22, Deubiquitinating Enzyme 22, KIAA1063, USP3L) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's USP22 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:50-1:100 FLISA: 1:1,000 WB: 1:100-1:500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the USP22 usp22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "USP22, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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