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Immunohistochemistry (IHC) (The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 46698(USP21 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200))

Rabbit anti-Human USP21 Polyclonal Antibody | anti-USP21 antibody

USP21 Antibody

Gene Names
USP21; USP16; USP23
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
USP21; Polyclonal Antibody; USP21 Antibody; USP16; USP23; anti-USP21 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total USP21 protein.
Purity/Purification
Antigen affinity purification
Form/Format
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.1mg/ml (varies by lot)
Sequence Length
1723
Applicable Applications for anti-USP21 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1: 40-200
Immunogen
Synthetic protein corresponding to residues near the C terminal of human USP21
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.

Immunohistochemistry (IHC)

(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 46698(USP21 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200))

Immunohistochemistry (IHC) (The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 46698(USP21 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200))
Related Product Information for anti-USP21 antibody
This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-USP21 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
61,122 Da
NCBI Official Full Name
Homo sapiens ubiquitin specific peptidase 21, mRNA
NCBI Official Synonym Full Names
ubiquitin specific peptidase 21
NCBI Official Symbol
USP21
NCBI Official Synonym Symbols
USP16; USP23
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase 21
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 21
UniProt Gene Name
USP21
UniProt Synonym Gene Names
USP23

NCBI Description

This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

Uniprot Description

Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination (). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates (PubMed:10799498). Deubiquitinates BAZ2A/TIP5 leading to its stabilization (PubMed:26100909).

Research Articles on USP21

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Product Notes

The USP21 usp21 (Catalog #AAA9429845) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The USP21 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's USP21 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1: 40-200. Researchers should empirically determine the suitability of the USP21 usp21 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "USP21, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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