Western Blot (WB)
(Western blot analysis of URG4 Antibody (Center) in CEM cell line lysates (35ug/lane). URG4 (arrow) was detected using the purified Pab.)
Rabbit anti-Human URG4 Polyclonal Antibody | anti-URGCP antibody
URG4, ID (URGCP, KIAA1507, URG4, Up-regulator of cell proliferation, HBV X protein up-regulated gene 4 protein, HBxAg up-regulated gene 4 protein)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Western Blot (WB)
(Western blot analysis of URG4 Antibody (Center) in CEM cell line lysates (35ug/lane). URG4 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of URG4 Antibody (Center) in CEM cell line lysates (35ug/lane). URG4 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(URG4 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the URG4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(URG4 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the URG4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
URG4 is upregulated in the presence of hepatitis B virus (HBV)-encoded X antigen (HBxAg) and may contribute to the development of hepatocellular carcinoma by promoting hepatocellular growth and survival (Tufan et al., 2002 [PubMed 12082552]).[supplied by OMIM, Mar 2008]
Uniprot Description
Function: May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer. Ref.1 Ref.7
Subcellular location: Cytoplasm. Nucleus. Note: In epithelial cells localized predominantly in the cytoplasm and occasionally in nuclei. Ref.1 Ref.7
Tissue specificity: Strongly expressed in hepatitis B virus-infected liver and in HCC cells. Also highly expressed in well-differentiated gastric cancer tissues and various gastric cancer cell lines. Ref.1 Ref.7
Induction: By HBxAg. Up-regulated in gastric cancer tissues and also in gastric cancer cell lines (at protein level). Ref.1 Ref.7
Sequence caution: The sequence BAA91312.1 differs from that shown. Reason: Erroneous initiation. The sequence BAA96031.1 differs from that shown. Reason: Erroneous initiation. The sequence CAE45880.1 differs from that shown. Reason: Erroneous initiation. The sequence CAH18244.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence CAH18244.1 differs from that shown. Reason: Frameshift at position 5.
Research Articles on URGCP
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Product Notes
The URGCP urgcp (Catalog #AAA648497) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The URG4, ID (URGCP, KIAA1507, URG4, Up-regulator of cell proliferation, HBV X protein up-regulated gene 4 protein, HBxAg up-regulated gene 4 protein) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's URG4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot, Immunohistochemistry Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100. Researchers should empirically determine the suitability of the URGCP urgcp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "URG4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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