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Western Blot (WB) (Western blot analysis of lysates from HepG2, U-87 MG cell line (from left to right), using URG4 Antibody (Center). MBS9208225 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)

Rabbit anti-Human URG4 Polyclonal Antibody | anti-URGCP antibody

URG4 Antibody (Center)

Gene Names
URGCP; URG4
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
URG4; Polyclonal Antibody; URG4 Antibody (Center); Up-regulator of cell proliferation; HBV X protein up-regulated gene 4 protein; HBxAg up-regulated gene 4 protein; URGCP; KIAA1507 {ECO:0000312|EMBL:BAA960311}; anti-URGCP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This URG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 466-495 amino acids from the Central region of human URG4.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
466-495
Sequence Length
888
Applicable Applications for anti-URGCP antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of lysates from HepG2, U-87 MG cell line (from left to right), using URG4 Antibody (Center). MBS9208225 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)

Western Blot (WB) (Western blot analysis of lysates from HepG2, U-87 MG cell line (from left to right), using URG4 Antibody (Center). MBS9208225 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)

Immunohistochemistry (IHC)

(URG4 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the URG4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (URG4 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the URG4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-URGCP antibody
URG4 is upregulated in the presence of hepatitis B virus (HBV)-encoded X antigen (HBxAg) and may contribute to the development of hepatocellular carcinoma by promoting hepatocellular growth and survival.
Product Categories/Family for anti-URGCP antibody
References
Huang, J., et al. Pathology 41(2):149-154(2009)
Song, J., et al. Neoplasia 8(12):995-1002(2006)
Tsang, H.T., et al. Genomics 88(3):333-346(2006)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
104987
NCBI Official Full Name
up-regulator of cell proliferation isoform 3
NCBI Official Synonym Full Names
upregulator of cell proliferation
NCBI Official Symbol
URGCP
NCBI Official Synonym Symbols
URG4
NCBI Protein Information
up-regulator of cell proliferation
UniProt Protein Name
Up-regulator of cell proliferation
UniProt Gene Name
URGCP
UniProt Entry Name
URGCP_HUMAN

NCBI Description

URG4 is upregulated in the presence of hepatitis B virus (HBV)-encoded X antigen (HBxAg) and may contribute to the development of hepatocellular carcinoma by promoting hepatocellular growth and survival (Tufan et al., 2002 [PubMed 12082552]).[supplied by OMIM, Mar 2008]

Uniprot Description

URG4: May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer. Induced by HBxAg. Up-regulated in gastric cancer tissues and also in gastric cancer cell lines (at protein level). 3 human isoforms produced by alternative splicing.

Chromosomal Location of Human Ortholog: 7p13

Cellular Component: cytoplasm; nucleus

Molecular Function: GTP binding

Biological Process: cell cycle

Research Articles on URGCP

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Product Notes

The URGCP urgcp (Catalog #AAA9208225) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 466-495. The URG4 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's URG4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). WB~~1:1000. Researchers should empirically determine the suitability of the URGCP urgcp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "URG4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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