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anti-Mouse uPAR IgG fraction, FITC labeled Polyclonal Antibody | anti-PLAUR antibody

Sheep anti mouse uPAR IgG fraction, FITC labeled

Gene Names
Plaur; Cd87; uPAR; u-PAR
Reactivity
Mouse
Applications
ELISA
Purity
IgG fraction
Synonyms
uPAR IgG fraction; FITC labeled; Polyclonal Antibody; Sheep anti mouse uPAR IgG fraction; anti-PLAUR antibody
Ordering
For Research Use Only!
Host
Host: Sheep; Source: Sheep serum
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
IgG fraction
Form/Format
Frozen liquid
Concentration
10.0 mg/ml (varies by lot)
Sequence Length
327
Applicable Applications for anti-PLAUR antibody
ELISA (EIA)
Immunogen
Recombinant full length mouse protein fused to a His tag at N-terminal end (Glycosylated).
Target Information
Recognizes soluble urokinase receptor (sUPAR)
Target Molecular Weight
33000
Buffer
0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6
Extinction Coefficient
1.36
Preparation and Storage
Store at -70 degree C; Protect from light. Shelf Life: 5 years from delivery
Related Product Information for anti-PLAUR antibody
FITC labeled polyclonal antibody (host sheep) to soluble mouse uPAR, His tagged. IgG fraction purified by immobilized Protein G. Licensed under United States Patent 5,519,120.
Product Categories/Family for anti-PLAUR antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
160,000
NCBI Official Full Name
urokinase plasminogen activator surface receptor
NCBI Official Synonym Full Names
plasminogen activator, urokinase receptor
NCBI Official Symbol
Plaur
NCBI Official Synonym Symbols
Cd87; uPAR; u-PAR
NCBI Protein Information
urokinase plasminogen activator surface receptor; urokinase plasminogen activator receptor; urokinase-type plasminogen activator receptor
UniProt Protein Name
Urokinase plasminogen activator surface receptor
UniProt Gene Name
Plaur
UniProt Synonym Gene Names
U-PAR; uPAR
UniProt Entry Name
UPAR_MOUSE

Uniprot Description

uPAR: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. Monomer (Probable). Interacts with MRC2. Interacts (via the UPAR/Ly6 domains) with SRPX2. Expressed in neurons of the rolandic area of the brain. Expressed in the brain. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, GPI anchor; Receptor, misc.

Cellular Component: focal adhesion; membrane; integral to plasma membrane; extracellular region; plasma membrane

Molecular Function: protein domain specific binding; protein binding; U-plasminogen activator receptor activity; enzyme binding; receptor binding

Biological Process: mesenchymal cell differentiation; negative regulation of apoptosis

Research Articles on PLAUR

Similar Products

Product Notes

The PLAUR plaur (Catalog #AAA135367) is an Antibody produced from Host: Sheep; Source: Sheep serum and is intended for research purposes only. The product is available for immediate purchase. The Sheep anti mouse uPAR IgG fraction, FITC labeled reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's uPAR IgG fraction, FITC labeled can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the PLAUR plaur for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "uPAR IgG fraction, FITC labeled, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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