Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 46319(ATG2A Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
Rabbit anti-Human ATG2A Polyclonal Antibody | anti-ATG2A antibody
ATG2A Antibody
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
ATG2A; Polyclonal Antibody; ATG2A Antibody; anti-ATG2A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total ATG2A protein.
Purity/Purification
Antigen affinity purification
Form/Format
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.7mg/ml (varies by lot)
Sequence Length
1938
Applicable Applications for anti-ATG2A antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1: 20-100
Immunogen
Synthetic peptide corresponding to internal residues of human ATG2A
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 46319(ATG2A Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 46319(ATG2A Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
Related Product Information for anti-ATG2A antibody
Atg2A (TG2 autophagy related 2 homolog A) is a 1, 938 amino acid protein that belongs to the ATG2 family and may play a role in vesicle assembly. Encoded by a gene that maps to human chromosome 11q13.1, Atg2A is conserved in chimpanzee, dog, cow, mouse and rat, and exists as four alternatively spliced isoforms. Undetected in adult tissues, including heart, brain, placenta, lung, liver and skeletal muscle, Atg2A regulation may act as a distinct indicator of autophagic programmed cell death. Atg2A is upregulated in both etoposide- and doxorubicin-induced apoptosis of HeLa cells, suggesting that Atg2A functions as a novel biomarker of topoisomerase II inhibitor-mediated apoptosis. Atg2A associates with Atg2B, indicating that these two related proteins also functionally interact. Atg2A frameshift mutations are linked to gastric and colorectal carcinomas with high microsatellite instability and may contribute to cancer development by deregulating the autophagy process. Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion.
Product Categories/Family for anti-ATG2A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
13,576 Da
NCBI Official Full Name
autophagy-related protein 2 homolog A
NCBI Official Synonym Full Names
autophagy related 2A
NCBI Official Symbol
ATG2A
NCBI Protein Information
autophagy-related protein 2 homolog A
UniProt Protein Name
Autophagy-related protein 2 homolog A
Protein Family
UniProt Gene Name
ATG2A
UniProt Synonym Gene Names
KIAA0404
Uniprot Description
Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion.
Research Articles on ATG2A
Similar Products
Product Notes
The ATG2A atg2a (Catalog #AAA9429467) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATG2A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ATG2A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1: 20-100. Researchers should empirically determine the suitability of the ATG2A atg2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATG2A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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