Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Dilution: WB - 1:2000All lanes: Anti-UGP2 Antibody (C-term) at 1:2000 dilution Lane 1: A2058 whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: Human liver lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 57 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit UGP2 Polyclonal Antibody | anti-UGP2 antibody

UGP2 Antibody (C-term)

Gene Names
UGP2; UDPG; UGP1; UDPGP; UGPP1; UGPP2; UDPGP2; pHC379
Reactivity
Human
Predicted: Bovine, Hamster, Mouse, Pig
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Synonyms
UGP2; Polyclonal Antibody; UGP2 Antibody (C-term); UTP--glucose-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; UGPase; UGP1; anti-UGP2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Bovine, Hamster, Mouse, Pig
Clonality
Polyclonal
Isotype
Ig
Specificity
This UGP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467-497 amino acids from the C-terminal region of human UGP2.
Purity/Purification
Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Form/Format
Supplied in PBS with 0.09% (W/V) sodium azide.
Sequence Length
497
Applicable Applications for anti-UGP2 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
Antigen Type
Synthetic Peptide
Antigen Source
Human
Antigen Region
467-497
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Dilution: WB - 1:2000All lanes: Anti-UGP2 Antibody (C-term) at 1:2000 dilution Lane 1: A2058 whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: Human liver lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 57 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (Dilution: WB - 1:2000All lanes: Anti-UGP2 Antibody (C-term) at 1:2000 dilution Lane 1: A2058 whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: Human liver lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 57 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)

Immunohistochemistry (IHC)

(Dilution: IHC-P - 1:10~50Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with UGP2 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (Dilution: IHC-P - 1:10~50Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with UGP2 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Related Product Information for anti-UGP2 antibody
UGP2 is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue,UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme.
Product Categories/Family for anti-UGP2 antibody
References
Ewing,R.M., Mol. Syst. Biol. 3, 89 (2007) Wistow,G., (er) Mol. Vis. 8, 205-220 (2002) Chang,H.Y., Eur. J. Biochem. 236 (2), 723-728 (1996)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
56940 Da
NCBI Official Full Name
UTP--glucose-1-phosphate uridylyltransferase isoform b
NCBI Official Synonym Full Names
UDP-glucose pyrophosphorylase 2
NCBI Official Symbol
UGP2
NCBI Official Synonym Symbols
UDPG; UGP1; UDPGP; UGPP1; UGPP2; UDPGP2; pHC379
NCBI Protein Information
UTP--glucose-1-phosphate uridylyltransferase
UniProt Protein Name
UTP--glucose-1-phosphate uridylyltransferase
UniProt Gene Name
UGP2
UniProt Synonym Gene Names
UGP1; UDPGP; UGPase
UniProt Entry Name
UGPA_HUMAN

NCBI Description

The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

UGP2: Plays a central role as a glucosyl donor in cellular metabolic pathways. Belongs to the UDPGP type 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - galactose; Carbohydrate Metabolism - pentose and glucuronate interconversions; Carbohydrate Metabolism - starch and sucrose; EC 2.7.7.9; Transferase

Chromosomal Location of Human Ortholog: 2p14-p13

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function: identical protein binding; protein binding; UTP:glucose-1-phosphate uridylyltransferase activity

Biological Process: glycogen biosynthetic process; glycogen metabolic process; UDP-glucuronate biosynthetic process

Research Articles on UGP2

Similar Products

Product Notes

The UGP2 ugp2 (Catalog #AAA9231354) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The UGP2 Antibody (C-term) reacts with Human Predicted: Bovine, Hamster, Mouse, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's UGP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA). Researchers should empirically determine the suitability of the UGP2 ugp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UGP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.