Western Blot (WB)
(Western blot analysis of TYW3 in A549 cell lysate with TYW3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Rabbit anti-Human, Mouse TYW3 Polyclonal Antibody | anti-TYW3 antibody
TYW3 Antibody
Gene Names
TYW3; C1orf171
Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
TYW3; Polyclonal Antibody; TYW3 Antibody; Radical S-adenosyl methionine and flavodoxin domain-containing protein 3; tRNA wybutosine-synthesizing protein 3 homolog; anti-TYW3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
TYW3 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW3 are known to exist; this antibody will detect both isoforms.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
226
Applicable Applications for anti-TYW3 antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against a 17 amino acid peptide near the center of human TYW3.
Target Name
TYW3
Preparation and Storage
Can be stored at 4 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of TYW3 in A549 cell lysate with TYW3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of TYW3 in A549 cell lysate with TYW3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-TYW3 antibody
TYW3 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.
Product Categories/Family for anti-TYW3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,104 Da
NCBI Official Full Name
tRNA wybutosine-synthesizing protein 3 homolog isoform 2
NCBI Official Synonym Full Names
tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
NCBI Official Symbol
TYW3
NCBI Official Synonym Symbols
C1orf171
NCBI Protein Information
tRNA wybutosine-synthesizing protein 3 homolog
UniProt Protein Name
tRNA wybutosine-synthesizing protein 3 homolog
Protein Family
UniProt Gene Name
TYW3
UniProt Synonym Gene Names
C1orf171; tRNA-yW-synthesizing protein 3
UniProt Entry Name
TYW3_HUMAN
NCBI Description
Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]
Uniprot Description
TYW3: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Belongs to the TYW3 family.
Protein type: EC 2.1.1.282; Methyltransferase
Chromosomal Location of Human Ortholog: 1p31.1
Molecular Function: methyltransferase activity
Biological Process: methylation; tRNA processing
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Product Notes
The TYW3 tyw3 (Catalog #AAA9403072) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TYW3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TYW3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the TYW3 tyw3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TYW3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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