Western Blot (WB)
(TXNL2 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TXNL2 antibody detected the TXNL2 protein (arrow).)
Rabbit anti-Human, Mouse TXNL2 Polyclonal Antibody | anti-TXNL2 antibody
TXNL2, NT (GLRX3, PICOT, TXNL2, Glutaredoxin-3, PKC-interacting cousin of thioredoxin, PKC-theta-interacting protein, Thioredoxin-like protein 2) (FITC)
Reactivity
Human, Mouse
Applications
Flow Cytometry, Functional Assay, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
TXNL2; Polyclonal Antibody; NT (GLRX3; PICOT; Glutaredoxin-3; PKC-interacting cousin of thioredoxin; PKC-theta-interacting protein; Thioredoxin-like protein 2) (FITC); GLRX3; Thioredoxin-like protein 2; anti-TXNL2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Applicable Applications for anti-TXNL2 antibody
Flow Cytometry (FC/FACS), FLISA, Western Blot (WB)
Application Notes
FC/FACS: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
TXNL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-118 amino acids from the N-terminal region of human TXNL2.
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(TXNL2 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TXNL2 antibody detected the TXNL2 protein (arrow).)
Western Blot (WB)
(TXNL2 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TXNL2 antibody detected the TXNL2 protein (arrow).)
Western Blot (WB)
(TXNL2 Antibody (N-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the TXNL2 antibody detected the TXNL2 protein (arrow).)
Western Blot (WB)
(TXNL2 Antibody (N-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the TXNL2 antibody detected the TXNL2 protein (arrow).)
Flow Cytometry (FC/FACS)
(TXNL2 Antibody (N-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(TXNL2 Antibody (N-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-TXNL2 antibody
GLRX3 is a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.
Product Categories/Family for anti-TXNL2 antibody
References
Ohayon, A., et al. J. Histochem. Cytochem. 58(9):799-806(2010). Haunhorst, P., et al. Biochem. Biophys. Res. Commun. 394(2):372-376(2010). Ohayon, A., et al. J Immunotoxicol 7(1):8-14(2010). Cha, M.K., et al. Cancer Epidemiol 33 (3-4), 281-287 (2009): Roeske, D., et al. Mol. Psychiatry (2009).
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
glutaredoxin-3 isoform 1
UniProt Protein Name
Glutaredoxin-3
UniProt Gene Name
GLRX3
UniProt Synonym Gene Names
PICOT; TXNL2; PICOT; PKCq-interacting protein
UniProt Entry Name
GLRX3_HUMAN
Uniprot Description
GLRX3: Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator. May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.
Protein type: Oxidoreductase
Chromosomal Location of Human Ortholog: 10q26
Cellular Component: cell cortex; Z disc
Molecular Function: protein binding; electron carrier activity; protein kinase C binding; metal ion binding; iron-sulfur cluster binding; protein disulfide oxidoreductase activity
Biological Process: cell redox homeostasis; regulation of the force of heart contraction
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Product Notes
The TXNL2 glrx3 (Catalog #AAA6360401) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TXNL2, NT (GLRX3, PICOT, TXNL2, Glutaredoxin-3, PKC-interacting cousin of thioredoxin, PKC-theta-interacting protein, Thioredoxin-like protein 2) (FITC) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TXNL2 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), FLISA, Western Blot (WB). FC/FACS: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the TXNL2 glrx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TXNL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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