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Western Blot (WB) (TXNL2 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TXNL2 antibody detected the TXNL2 protein (arrow).)

Rabbit anti-Human, Mouse TXNL2 Polyclonal Antibody | anti-Glrx3 antibody

TXNL2, NT (GLRX3, PICOT, TXNL2, Glutaredoxin-3, PKC-interacting cousin of thioredoxin, PKC-theta-interacting protein, Thioredoxin-like protein 2)

Gene Names
Glrx3; PICOT; Txnl2
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Flow Cytometry, Functional Assay
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
TXNL2; Polyclonal Antibody; NT (GLRX3; PICOT; Glutaredoxin-3; PKC-interacting cousin of thioredoxin; PKC-theta-interacting protein; Thioredoxin-like protein 2); Anti -TXNL2; anti-Glrx3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Human, mouse
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-Glrx3 antibody
ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in Western Blot, Flow Cytometry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Flow Cytometry: 1:10-50
Immunogen
TXNL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-118 amino acids from the N-terminal region of human TXNL2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(TXNL2 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TXNL2 antibody detected the TXNL2 protein (arrow).)

Western Blot (WB) (TXNL2 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TXNL2 antibody detected the TXNL2 protein (arrow).)

Western Blot (WB)

(TXNL2 Antibody (N-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the TXNL2 antibody detected the TXNL2 protein (arrow).)

Western Blot (WB) (TXNL2 Antibody (N-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the TXNL2 antibody detected the TXNL2 protein (arrow).)

Flow Cytometry (FC/FACS)

(TXNL2 Antibody (N-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (TXNL2 Antibody (N-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-Glrx3 antibody
GLRX3 is a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.
Product Categories/Family for anti-Glrx3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
37,849 Da
NCBI Official Full Name
thioredoxin-like 2, isoform CRA_d
NCBI Official Synonym Full Names
glutaredoxin 3
NCBI Official Symbol
Glrx3
NCBI Official Synonym Symbols
PICOT; Txnl2
NCBI Protein Information
glutaredoxin-3; thioredoxin-like 2; PKCq-interacting protein; thioredoxin-like protein 2; PKC-theta-interacting protein; PKC-interacting cousin of thioredoxin
UniProt Protein Name
Glutaredoxin-3
Protein Family
UniProt Gene Name
Glrx3
UniProt Synonym Gene Names
Picot; Txnl2; PICOT
UniProt Entry Name
GLRX3_RAT

NCBI Description

interacts with Protein kinase C-theta; involved in the inhibition of c-Jun N-terminal kinase activation [RGD, Feb 2006]

Uniprot Description

GLRX3: Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator. May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.

Protein type: Oxidoreductase

Cellular Component: dendrite; cell cortex; Z disc; nucleus

Molecular Function: electron carrier activity; protein kinase C binding; metal ion binding; protein disulfide oxidoreductase activity; iron-sulfur cluster binding

Biological Process: cell redox homeostasis; regulation of the force of heart contraction

Research Articles on Glrx3

Similar Products

Product Notes

The Glrx3 glrx3 (Catalog #AAA6011477) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TXNL2, NT (GLRX3, PICOT, TXNL2, Glutaredoxin-3, PKC-interacting cousin of thioredoxin, PKC-theta-interacting protein, Thioredoxin-like protein 2) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TXNL2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS). Suitable for use in Western Blot, Flow Cytometry, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Flow Cytometry: 1:10-50. Researchers should empirically determine the suitability of the Glrx3 glrx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TXNL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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