Western Blot (WB)
(Western Blot (WB) analysis of TXNL1 polyclonal antibody at 1:1000 dilutionLane1:HepG2 whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:The Spleen tissue lysate of Mouse (40ug) Lane4:The Spleen tissue lysate of Rat (40ug))
Rabbit TXNL1 Polyclonal Antibody | anti-TXNL1 antibody
TXNL1 Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
TXNL1; Polyclonal Antibody; TXNL1 Polyclonal Antibody; Thioredoxin-like protein 1; 32 kDa thioredoxin-related protein; TRP32; TXL; TXNL; anti-TXNL1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
TXNL1 polyclonal antibody detects endogenous levels of TXNL1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
289
Applicable Applications for anti-TXNL1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200
IHC: 1:50-1:200
IF: 1:50-1:200
Immunogen
Recombinant TXNL1 protein, corresponding to amino acids 1-289 of Human LGR5.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of TXNL1 polyclonal antibody at 1:1000 dilutionLane1:HepG2 whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:The Spleen tissue lysate of Mouse (40ug) Lane4:The Spleen tissue lysate of Rat (40ug))
Western Blot (WB)
(Western Blot (WB) analysis of TXNL1 polyclonal antibody at 1:1000 dilutionLane1:HepG2 whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:The Spleen tissue lysate of Mouse (40ug) Lane4:The Spleen tissue lysate of Rat (40ug))
Related Product Information for anti-TXNL1 antibody
Thioredoxins are small redox active proteins that play a variety of roles throughout the cell. TXNL1 (Thioredoxin-like protein 1), also known as TRP32, TXL or TXL-1, is a 289 amino acid cytoplasmic protein that is thought to participate in endocytotic signaling pathways and may act as a redox sensor. Expressed throughout the body, TXNL1 functions to couple oxidative stress to endocytosis, thereby regulating the GDI: Rad5-mediated endocytic response. Additionally, overexpression of TXNL1 inhibits cell proliferation by predisposing the cell to G0/G1 arrest, suggesting that TXNL1 also functions as a transcriptional repressor. TXNL1 shares 99% homology with its mouse homolog and contains one thioredoxin domain.
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
~ 32kDa
NCBI Official Full Name
Thioredoxin-like protein 1
UniProt Protein Name
Thioredoxin-like protein 1
Protein Family
UniProt Gene Name
TXNL1
UniProt Synonym Gene Names
TRP32; TXL; TXNL
UniProt Entry Name
TXNL1_HUMAN
Uniprot Description
TXNL1: a thiol reductase and novel subunit of the proteasome 19S particle. Interconverts reduced sulfide groups and oxidized disulfide bonds in a substrate.
Protein type: Oxidoreductase
Chromosomal Location of Human Ortholog: 18q21.31
Cellular Component: proteasome complex; cytoplasm; nucleus
Molecular Function: disulfide oxidoreductase activity; protein disulfide oxidoreductase activity
Biological Process: cell redox homeostasis; glycerol ether metabolic process
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Product Notes
The TXNL1 txnl1 (Catalog #AAA3011507) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TXNL1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TXNL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the TXNL1 txnl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TXNL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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