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Western Blot (WB)
(Anti-TXNL1 rabbit polyclonal antibody at 1:500 dilution Lane A: HL-60 Whole Cell Lysate Lane B: Caco2 Whole Cell Lysate Lane C: K562 Whole Cell Lysate Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:32 kDa)
Rabbit TXNL1 Polyclonal Antibody | anti-TXNL1 antibody
Anti-TXNL1 Antibody, Rabbit Polyclonal
Gene Names
TXNL1; Txl; TXNL; TRP32; TXL-1; HEL-S-114
Reactivity
Human, MousePredicted to React with: Rat (Species predicted to react based on 100% sequence homology)
Applications
Western Blot, Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
TXNL1; Polyclonal Antibody; Anti-TXNL1 Antibody; Rabbit Polyclonal; TXNL1 Antibody; Rabbit PAb; Antigen Affinity Purified; thioredoxin-like 1; Anti-HEL-S-114 Antibody; Anti-TRP32 Antibody; Anti-Txl Antibody; Anti-TXL-1 Antibody; Anti-TXNL Antibody; anti-TXNL1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Predicted to React with: Rat (Species predicted to react based on 100% sequence homology)
Predicted to React with: Rat (Species predicted to react based on 100% sequence homology)
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human TXNL1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-TXNL1 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:500-1:2000
IHC-P: 1:200-1:1000
IHC-P: 1:200-1:1000
Immunogen
A synthetic peptide corresponding to the center region of the Human TXNL1
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human TXNL1, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Western Blot (WB)
(Anti-TXNL1 rabbit polyclonal antibody at 1:500 dilution Lane A: HL-60 Whole Cell Lysate Lane B: Caco2 Whole Cell Lysate Lane C: K562 Whole Cell Lysate Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:32 kDa)
Western Blot (WB)
(Anti-TXNL1 rabbit polyclonal antibody at 1:500 dilution Lane A: HL-60 Whole Cell Lysate Lane B: Caco2 Whole Cell Lysate Lane C: K562 Whole Cell Lysate Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:32 kDa)
Immunohistochemistry (IHC)
(Immunochemical staining TXNL1 in human thyroid carcinoma with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining TXNL1 in human thyroid carcinoma with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining TXNL1 in human small intestine with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining TXNL1 in human small intestine with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining TXNL1 in mouse small intestine with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining TXNL1 in mouse small intestine with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-TXNL1 antibody
Thioredoxin-like protein, or TXNL1 is a two-domain of 32kDa protein composed of an N-terminal Trx domain and a C-terminal domain that interacts with the 26S proteasome. TXNL1 is abundant, metabolically stable, and widely expressed and is present in the cytoplasm and nucleus. TXNL1 has thioredoxin activity with a redox potential of about -250 mV. TXNL1 plays a selective role in the regulation of fluid phase endocytosis, by controlling Guanine Nucleotide Dissociation Inhibitor (GDI) capacity to capture Rab5.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
289
NCBI Official Full Name
Thioredoxin-like protein 1
NCBI Official Synonym Full Names
thioredoxin-like 1
NCBI Official Symbol
TXNL1
NCBI Official Synonym Symbols
Txl; TXNL; TRP32; TXL-1; HEL-S-114
NCBI Protein Information
thioredoxin-like protein 1; thioredoxin-related protein 1; 32 kDa thioredoxin-related protein; thioredoxin-related 32 kDa protein; epididymis secretory protein Li 114
UniProt Protein Name
Thioredoxin-like protein 1
Protein Family
UniProt Gene Name
TXNL1
UniProt Synonym Gene Names
TRP32; TXL; TXNL
UniProt Entry Name
TXNL1_HUMAN
Uniprot Description
TXNL1: a thiol reductase and novel subunit of the proteasome 19S particle. Interconverts reduced sulfide groups and oxidized disulfide bonds in a substrate.
Protein type: Oxidoreductase
Chromosomal Location of Human Ortholog: 18q21.31
Cellular Component: proteasome complex; cytoplasm; nucleus
Molecular Function: disulfide oxidoreductase activity; protein disulfide oxidoreductase activity
Biological Process: cell redox homeostasis; glycerol ether metabolic process
Research Articles on TXNL1
Similar Products
Product Notes
The TXNL1 txnl1 (Catalog #AAA8104165) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TXNL1 Antibody, Rabbit Polyclonal reacts with Human, Mouse Predicted to React with: Rat (Species predicted to react based on 100% sequence homology) and may cross-react with other species as described in the data sheet. AAA Biotech's TXNL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000 IHC-P: 1:200-1:1000. Researchers should empirically determine the suitability of the TXNL1 txnl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TXNL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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