Rabbit anti-Human TXNDC6 Polyclonal Antibody | anti-NME9 antibody

TXNDC6, ID (NME9, TXL2, TXNDC6, Thioredoxin domain-containing protein 6, Thioredoxin-like protein 2)

Cat. Num. AAA6002211

• Gene Names: NME9; TXL2; TXL-2; TXNDC6; NM23-H9
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: TXNDC6; Polyclonal Antibody; ID (NME9; TXL2; Thioredoxin domain-containing protein 6; Thioredoxin-like protein 2); Anti -TXNDC6; anti-NME9 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-NME9 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Western Blot, Immunohistochemistry, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Immunohistochemistry: 1:50-100
• Immunogen: TXNDC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the Central region of human TXNDC6.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(TXNDC6 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TXNDC6 antibody detected the TXNDC6 protein (arrow).)

Western Blot (WB)

(Western blot analysis of TXNDC6 (arrow) using rabbit polyclonal TXNDC6 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TXNDC6 gene.)

Immunohistochemistry (IHC)

(TXNDC6 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TXNDC6 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-NME9 antibody

May be a regulator of microtubule physiology.

Product Categories/Family for anti-NME9 antibody

Antibodies; Abs to Thioredoxin

NCBI and Uniprot Product Information

• NCBI GI #: 30023828
• NCBI GeneID: 347736
• NCBI Accession #: NP_835231.1
• NCBI GenBank Nucleotide #: NM_178130.2
• UniProt Accession #: Q86XW9; Q7Z4A8; Q8N1V7
• Molecular Weight: 36,856 Da
• NCBI Official Full Name: thioredoxin domain-containing protein 6
• NCBI Official Synonym Full Names: NME/NM23 family member 9
• NCBI Official Symbol: NME9
• NCBI Official Synonym Symbols: TXL2; TXL-2; TXNDC6; NM23-H9
• NCBI Protein Information: thioredoxin domain-containing protein 6; thioredoxin-like 2; NME family member 9; NME gene family member 9; thioredoxin-like protein 2; thioredoxin domain containing 6
• UniProt Protein Name: Thioredoxin domain-containing protein 6
• Protein Family: Thioredoxin domain-containing protein
• UniProt Gene Name: NME9
• UniProt Synonym Gene Names: TXL2; TXNDC6; Txl-2
• UniProt Entry Name: TXND6_HUMAN

Uniprot Description

Function: May be a regulator of microtubule physiology.

Subunit structure: Monomer and homodimer.

Subcellular location: Cytoplasm

By similarity. Cytoplasm › cytoskeleton

By similarity. Note: Associated with microtubules. Detected in cilia of lung epithelium, and associated with the spermatid tail and manchette

By similarity. Ref.1

Tissue specificity: Detected at very low levels in testis, lung and brain. Ref.1

Miscellaneous: Shows no detectable enzyme activity.

Sequence similarities: Belongs to the NDK family.Contains 1 thioredoxin domain.