Mouse anti-Human FOXQ1 Monoclonal Antibody | anti-FOXQ1 antibody

Mouse Monoclonal [clone 2E2] (IgG2b,k) to Human FOXQ1

Cat. Num. AAA246550

• Gene Names: FOXQ1; HFH1
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA
• Purity: Protein A Purified
• Synonyms: FOXQ1; Monoclonal Antibody; Mouse Monoclonal [clone 2E2] (IgG2b; k) to Human FOXQ1; Anti-FOXQ1 Antibody (clone 2E2) IHC-plus; Forkhead box Q1; HFH-1; HNF-3/forkhead-like protein 1; HFH1; Forkhead box protein Q1; Human FOXQ1; anti-FOXQ1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2b,k
• Clone Number: 2E2
• Specificity: Human FOXQ1
• Purity/Purification: Protein A Purified
• Form/Format: PBS, pH 7.2
• Concentration: 0.33 mg/ml (varies by lot)
• Sequence Length: 403

• Applicable Applications for anti-FOXQ1 antibody: Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
• Application Notes: ELISA, IHC-P (5 ug/ml); Usage: Sandwich ELISA: Recombinant protein.
• Target Species: Human
• Immunogen Description: Recombinant protein
• Immunogen Type: Recombinant protein
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.

Immunohistochemistry (IHC)

(Anti-FOXQ1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

ELISA (EIA)

(Detection limit for recombinant GST tagged FOXQ1 is 3 ng/ml as a capture antibody.)

NCBI and Uniprot Product Information

• NCBI GI #: 145309320
• NCBI GeneID: 94234
• NCBI Accession #: NP_150285.3
• NCBI GenBank Nucleotide #: NM_033260.3
• UniProt Accession #: Q9C009; Q9NS06
• Molecular Weight: 41,526 Da
• NCBI Official Full Name: forkhead box protein Q1
• NCBI Official Synonym Full Names: forkhead box Q1
• NCBI Official Symbol: FOXQ1
• NCBI Official Synonym Symbols: HFH1
• NCBI Protein Information: forkhead box protein Q1; HFH-1; HNF-3/forkhead-like protein 1; winged helix/forkhead transcription factor; hepatocyte nuclear factor 3 forkhead homolog 1
• UniProt Protein Name: Forkhead box protein Q1
• Protein Family: Forkhead box protein
• UniProt Gene Name: FOXQ1
• UniProt Synonym Gene Names: HFH1; HFH-1
• UniProt Entry Name: FOXQ1_HUMAN

NCBI Description

FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).[supplied by OMIM, May 2009]

Uniprot Description

FOXQ1: Plays a role in hair follicle differentiation.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 6p25

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; hair follicle morphogenesis