Rabbit anti-Mouse TWIST2 Polyclonal Antibody | anti-TWIST2 antibody
Anti-TWIST2 (Twist-related Protein 2, Class A Basic Helix-loop-helix Protein 39, bHLHa39, Dermis-expressed Protein 1, Dermo-1, BHLHA39, DERMO1)
Gene Names
TWIST2; DERMO1; bHLHa39; MGC117334
Reactivity
Mouse
Applications
ELISA, Western Blot
Purity
Affinity Purified
Synonyms
TWIST2; Polyclonal Antibody; Anti-TWIST2 (Twist-related Protein 2; Class A Basic Helix-loop-helix Protein 39; bHLHa39; Dermis-expressed Protein 1; Dermo-1; BHLHA39; DERMO1); Twist-related Protein 2; DERMO1; anti-TWIST2 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes mouse Twist2.
Purity/Purification
Affinity Purified
Form/Format
Supplied as a liquid in PBS, 0.1% BSA.
Concentration
~1mg/ml (varies by lot)
Applicable Applications for anti-TWIST2 antibody
ELISA; Western Blot
Application Notes
Recommended Dilutions: ELISA: 1:100,000 (50-100ng control peptide/well)
Western Blot: 1-10ug/ml
Western Blot: 1-10ug/ml
Immunogen
Synthetic peptide corresponding to 20aa mouse Twist2, N-terminal (KLH).
Source Information
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Temperature: Blue Ice
Shipping Temperature: Blue Ice
Related Product Information for anti-TWIST2 antibody
Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by Twist gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Twist. It is thought that during osteoblast development this protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype.
Twist and Dermo1, also called Twist1 and Twist2 respectively, were induced by a cytokine signaling pathway that required the dorsal-related protein Rela, a member of the nuclear factor kappa-B family of transcription factors, in mice. Twist1 and Twist2 repressed cytokine gene expression through interaction with Rela. TWIST proteins regulate cytokine signaling by establishing a negative feedback loop that represses the NFKB-dependent cytokine pathway.
Twist and Dermo1, also called Twist1 and Twist2 respectively, were induced by a cytokine signaling pathway that required the dorsal-related protein Rela, a member of the nuclear factor kappa-B family of transcription factors, in mice. Twist1 and Twist2 repressed cytokine gene expression through interaction with Rela. TWIST proteins regulate cytokine signaling by establishing a negative feedback loop that represses the NFKB-dependent cytokine pathway.
Product Categories/Family for anti-TWIST2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
18,124 Da
NCBI Official Full Name
twist-related protein 2
NCBI Official Synonym Full Names
twist homolog 2 (Drosophila)
NCBI Official Symbol
TWIST2
NCBI Official Synonym Symbols
DERMO1; bHLHa39; MGC117334
NCBI Protein Information
twist-related protein 2; OTTHUMP00000235137; dermis-expressed protein 1; twist-related bHLH protein Dermo1; class A basic helix-loop-helix protein 39
UniProt Protein Name
Twist-related protein 2
Protein Family
UniProt Gene Name
TWIST2
UniProt Synonym Gene Names
BHLHA39; DERMO1
UniProt Entry Name
TWST2_HUMAN
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Product Notes
The TWIST2 twist2 (Catalog #AAA629033) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TWIST2 (Twist-related Protein 2, Class A Basic Helix-loop-helix Protein 39, bHLHa39, Dermis-expressed Protein 1, Dermo-1, BHLHA39, DERMO1) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TWIST2 can be used in a range of immunoassay formats including, but not limited to, ELISA; Western Blot. Recommended Dilutions: ELISA: 1:100,000 (50-100ng control peptide/well) Western Blot: 1-10ug/ml. Researchers should empirically determine the suitability of the TWIST2 twist2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TWIST2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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