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Rabbit TUT1 Polyclonal Antibody | anti-TUT1 antibody

TUT1 antibody

Gene Names
TUT1; PAPD2; RBM21; URLC6; TUTase; STARPAP
Applications
Western Blot
Synonyms
TUT1; Polyclonal Antibody; TUT1 antibody; Polyclonal TUT1; Anti-TUT1; TUTase; TUT 1; RBM21; TUT-1; FLJ21850; FLJ22267; FLJ22347; terminal uridylyl transferase 1; MGC131987; MGC149809; PAPD2; U6 snRNA-specific; anti-TUT1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Form/Format
Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration
1 mg/ml (varies by lot)
Sequence Length
578
Applicable Applications for anti-TUT1 antibody
Western Blot (WB)
Application Notes
WB: 0.2-1 ug/ml
Biological Significance
TUT1 is a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly(A) polymerase. TUT1 specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation. TUT1 specifically catalyzes uridylylation of U6 snRNA and is essential for cell proliferation.
Cross-Reactivity
Human
Immunogen
TUT1 antibody was raised in rabbit using the middle region of TUT1 as the immunogen
Preparation and Storage
Store at 4 degree C, following reconstitution, aliquot and store at -20 degree C. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-TUT1 antibody
Affinity purified rabbit polyclonal TUT1 antibody
Product Categories/Family for anti-TUT1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
93,847 Da
NCBI Official Full Name
TUT1 protein, partial
NCBI Official Synonym Full Names
terminal uridylyl transferase 1, U6 snRNA-specific
NCBI Official Symbol
TUT1
NCBI Official Synonym Symbols
PAPD2; RBM21; URLC6; TUTase; STARPAP
NCBI Protein Information
speckle targeted PIP5K1A-regulated poly(A) polymerase
UniProt Protein Name
Speckle targeted PIP5K1A-regulated poly(A) polymerase
UniProt Gene Name
TUT1
UniProt Synonym Gene Names
RBM21; Star-PAP; RNA-binding protein 21; U6-TUTase
UniProt Entry Name
STPAP_HUMAN

NCBI Description

This gene encodes a nucleotidyl transferase that functions as both a terminal uridylyltransferase and a nuclear poly(A) polymerase. The encoded enzyme specifically adds and removes nucleotides from the 3' end of small nuclear RNAs and select mRNAs and may function in controlling gene expression and cell proliferation.[provided by RefSeq, Apr 2009]

Uniprot Description

RBM21: Highly specific terminal uridylyltransferase that exclusively accepts U6 snRNA as substrate. U6 snRNA is unique in that nucleotides are both added to and removed from its 3'-end. U6-TUTase is responsible for a controlled elongation reaction that results in the restoration of the four 3'-terminal UMP-residues found in newly transcribed U6 snRNA. Does not play a role in replication-dependent histone mRNA degradation.

Protein type: EC 2.7.7.19; EC 2.7.7.52; Nucleolus; Transferase

Chromosomal Location of Human Ortholog: 11q12.2

Cellular Component: nucleoplasm; intercellular bridge; nucleolus; nuclear speck; mRNA cleavage and polyadenylation specificity factor complex

Molecular Function: polynucleotide adenylyltransferase activity; protein binding; enzyme binding; mRNA 3'-UTR binding; RNA binding; metal ion binding; RNA uridylyltransferase activity; ATP binding

Biological Process: snRNA processing; mRNA polyadenylation; mRNA cleavage

Research Articles on TUT1

Similar Products

Product Notes

The TUT1 tut1 (Catalog #AAA5303368) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TUT1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.2-1 ug/ml. Researchers should empirically determine the suitability of the TUT1 tut1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TUT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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