Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7130067(TTBK2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))
Rabbit anti-Human, Mouse TTBK2 Polyclonal Antibody | anti-TTBK2 antibody
TTBK2 Antibody
IHC: 1:30-1:150
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7130067(TTBK2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7130067(TTBK2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7130067(TTBK2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7130067(TTBK2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in this gene cause spinocerebellar ataxia type 11 (SCA11); a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem. [provided by RefSeq, Aug 2009]
Uniprot Description
TTBK2: Serine/threonine kinase which is able to phosphorylate tau on serines. Defects in TTBK2 are the cause of spinocerebellar ataxia type 11 (SCA11). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA11 is an autosomal dominant cerebellar ataxia (ADCA). It is a relatively benign, late-onset, slowly progressive neurologic disorder. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.7.11.1; Protein kinase, CK1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; CK1 group; TTBK family
Chromosomal Location of Human Ortholog: 15q15.2
Cellular Component: centriole; extracellular space; cytosol; nucleus
Molecular Function: protein serine/threonine kinase activity; protein binding; ATP binding
Biological Process: regulation of cell shape; peptidyl-serine phosphorylation; smoothened signaling pathway; organelle organization and biogenesis; cilium biogenesis
Disease: Spinocerebellar Ataxia 11
Research Articles on TTBK2
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Product Notes
The TTBK2 ttbk2 (Catalog #AAA7130067) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TTBK2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TTBK2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). ELISA: 1:2000-1:10000 IHC: 1:30-1:150. Researchers should empirically determine the suitability of the TTBK2 ttbk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TTBK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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