Western Blot (WB)
(Anti- TRP 7 Picoband antibody, MBS178261, Western blottingAll lanes: Anti TRP 7 (MBS178261) at 0.5ug/mlWB: Recombinant Human TRP 7 Protein 0.5ngPredicted bind size: 39KDObserved bind size: 39KD )
anti-Human, Mouse TRP 7 Polyclonal Antibody | anti-TRP 7 antibody
Anti-TRP 7 Antibody
Gene Names
TRPC7; TRP7
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Immunogen Affinity Purified
Synonyms
TRP 7; Polyclonal Antibody; Anti-TRP 7 Antibody; Short transient receptor potential channel 7; Capacitative calcium channel TRPC7; cation channel; subfamily C; member 7; hTRP7; KNP3; Likley ortholog of mouse transient receptor potential cation channel subfamily C member 7; mTRP7; Putative capacitative calcium channel; Transient receptor potential cation channel subfamily C member 7; transient receptor potential-related channel 7; a novel putative Ca2+ channel protein; Transient receptor protein 7; TRP-7; TRP7 protein; TRPC 7; TRPC7; Trpc7 transient receptor potential cation channel; TRPC7_HUMAN; TRPM2; Trrp8; transient receptor potential cation channel; anti-TRP 7 antibody
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Immunogen Affinity Purified
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
746
Applicable Applications for anti-TRP 7 antibody
Western Blot (WB)
Application Notes
Western Blot Concentration: 0.1-0.5ug/ml
Immunogen
E Coli-derived human TRP 7 recombinant protein (Position: K716-I862). Human TRP 7 shares 95% amino acid (aa) sequence identity with mouse TRP 7.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Western Blot (WB)
(Anti- TRP 7 Picoband antibody, MBS178261, Western blottingAll lanes: Anti TRP 7 (MBS178261) at 0.5ug/mlWB: Recombinant Human TRP 7 Protein 0.5ngPredicted bind size: 39KDObserved bind size: 39KD )
Western Blot (WB)
(Anti- TRP 7 Picoband antibody, MBS178261, Western blottingAll lanes: Anti TRP 7 (MBS178261) at 0.5ug/mlWB: Recombinant Human TRP 7 Protein 0.5ngPredicted bind size: 39KDObserved bind size: 39KD )
Western Blot (WB)
(Anti- TRP 7 Picoband antibody, MBS178261, Western blottingAll lanes: Anti TRP 7 (MBS178261) at 0.5ug/mlLane 1: Mouse Brain Tissue Lysate at 50ugLane 2: A549 Whole Cell Lysate at 40ugLane 3: COLO320 Whole Cell Lysate at 40ugLane 4: SKOV Whole Cell Lysate at 40ugPredicted bind size: 99KDObserved bind size: 99KD )
Western Blot (WB)
(Anti- TRP 7 Picoband antibody, MBS178261, Western blottingAll lanes: Anti TRP 7 (MBS178261) at 0.5ug/mlLane 1: Mouse Brain Tissue Lysate at 50ugLane 2: A549 Whole Cell Lysate at 40ugLane 3: COLO320 Whole Cell Lysate at 40ugLane 4: SKOV Whole Cell Lysate at 40ugPredicted bind size: 99KDObserved bind size: 99KD )
Related Product Information for anti-TRP 7 antibody
Description: Rabbit IgG polyclonal antibody for Short transient receptor potential channel 7(TRPC7) detection. Tested with WB in Human;Mouse.
Background: Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a human gene encoding a protein of the same name. Using a cosmid/BAC contig, this gene is mapped to chromosome 21q22.3. TRPC7 is the most abundantly expressed long TRPC in peripheral blood and in some blood cell lines. The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death.
Background: Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a human gene encoding a protein of the same name. Using a cosmid/BAC contig, this gene is mapped to chromosome 21q22.3. TRPC7 is the most abundantly expressed long TRPC in peripheral blood and in some blood cell lines. The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death.
References
1. Du, J., Xie, J., Yue, L. Intracellular calcium activates TRPM2 and its alternative spliced isoforms. Proc. Nat. Acad. Sci. 106: 7239-7244, 2009. 2. Farooqi, A. A., Javeed, M. K., Javed, Z., Riaz, A. M., Mukhtar, S., Minhaj, S., Abbas, S., Bhatti, S. TRPM channels: same ballpark, different players, and different rules in immunogenetics. Immunogenetics 63: 773-787, 2011. 3. McQuillin, A., Bass, N. J., Kalsi, G., Lawrence, J., Puri, V., Choudhury, K., Detera-Wadleigh, S. D., Curtis, D., Gurling, H. M. D. Fine mapping of a susceptibility locus for bipolar and genetically related unipolar affective disorders, to a region containing the C21ORF29 and TRPM2 genes on chromosome 21q22.3. Molec. Psychiat. 11: 134-142, 2006.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
92,429 Da
NCBI Official Full Name
short transient receptor potential channel 7 isoform 3
NCBI Official Synonym Full Names
transient receptor potential cation channel subfamily C member 7
NCBI Official Symbol
TRPC7
NCBI Official Synonym Symbols
TRP7
NCBI Protein Information
short transient receptor potential channel 7
UniProt Protein Name
Short transient receptor potential channel 7
UniProt Gene Name
TRPC7
UniProt Synonym Gene Names
TRP7; TrpC7; TRP-7; hTRP7
UniProt Entry Name
TRPC7_HUMAN
Uniprot Description
TRPC7: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG). May also be activated by intracellular calcium store depletion. Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC7 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Channel, calcium; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 5q31.1
Cellular Component: cis-Golgi network; integral to plasma membrane; nuclear envelope; perinuclear region of cytoplasm; plasma membrane
Molecular Function: calcium channel activity; protein binding; store-operated calcium channel activity
Biological Process: cytosolic calcium ion homeostasis; manganese ion transport; platelet activation; single fertilization
Research Articles on TRP 7
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Product Notes
The TRP 7 trpc7 (Catalog #AAA178261) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-TRP 7 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TRP 7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot Concentration: 0.1-0.5ug/ml. Researchers should empirically determine the suitability of the TRP 7 trpc7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRP 7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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