Rabbit anti-Human TROY Polyclonal Antibody | anti-TROY antibody

Anti-TROY Antibody

Cat. Num. AAA8308441

• Gene Names: TNFRSF19; TAJ; TROY; TRADE; TAJ-alpha
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Immunogen Affinity Chromatography
• Synonyms: TROY; Polyclonal Antibody; Anti-TROY Antibody; TAJ; Tumor necrosis factor receptor superfamily member 19; TRADE; Toxicity and JNK inducer; anti-TROY antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Recognizes endogenous levels of TROY protein.
• Purity/Purification: Purified by Immunogen Affinity Chromatography
• Form/Format: Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.

• Applicable Applications for anti-TROY antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Recombinant fusion protein of human TROY. The exact sequence is proprietary.
• Preparation and Storage: Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of TROY expression in HeLa (A) whole cell lysates.)

Related Product Information for anti-TROY antibody

Rabbit polyclonal antibody to TROY

NCBI and Uniprot Product Information

• NCBI GI #: 325120959
• NCBI GeneID: 55504
• NCBI Accession #: NP_001191387.1
• NCBI GenBank Nucleotide #: NM_001204458.1
• UniProt Accession #: Q9NS68; Q9BXZ9; Q9BY00; Q9NZV2; A8KA09; A8KA26; B1AM40; B1AM41; B4E2I6
• Molecular Weight: 30,542 Da
• NCBI Official Full Name: tumor necrosis factor receptor superfamily member 19 isoform 2
• NCBI Official Synonym Full Names: TNF receptor superfamily member 19
• NCBI Official Symbol: TNFRSF19
• NCBI Official Synonym Symbols: TAJ; TROY; TRADE; TAJ-alpha
• NCBI Protein Information: tumor necrosis factor receptor superfamily member 19
• UniProt Protein Name: Tumor necrosis factor receptor superfamily member 19
• UniProt Gene Name: TNFRSF19
• UniProt Synonym Gene Names: TAJ; TROY

NCBI Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

TNFRSF19: Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q12.12

Cellular Component: plasma membrane

Molecular Function: receptor activity

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; tissue development